Metallo is depicted as a cyborg with a kryptonite power source in his heart, which he uses as a weapon against Superman. In 2009, Metallo was ranked as IGN's 52nd Greatest Comic Book Villain of All Time.
Metallo in Action Comics Annual #10 (March 2007)
Art by Art Adams and Alex Sinclair
|First appearance||Action Comics #252 (May 1959)|
|Created by||Robert Bernstein |
|Alter ego||John Corben|
|Notable aliases||Metal Zero (Metal-0)|
|Abilities||current: Bionic Surgery
Metallo was created by Robert Bernstein and Al Plastino and debuted in Action Comics #252 (May 1959). John Corben and Metallo first appeared in the daily newspaper strip called "The Menace of Metallo", which ran from 15 December 1958 to 4 April 1959.
There was an earlier "Metalo" who appeared in World's Finest #6 (Summer 1942). This was just a man who discovered the most powerful metal on earth and invented a strength serum.
The Golden Age Superman battled an unnamed scientist calling himself Metalo who wore a powered suit of steel armor. Years later, Superman encountered the villain a second time. Metalo (now named George Grant) had a new suit of armor and had also taken a serum to increase his strength to superhuman levels. He exposed Superman to a ray that reduced his power significantly giving Metalo superior strength in their first battle. Superman engaged in a lengthy regimen of exercise and training to restore his powers and returned to easily defeat Metalo.
A different Metallo appeared as Jor-El's robot to battle Superboy in Superboy #49 (1956).
John Corben was originally a journalist (and secretly a thief and murderer) who had just committed what he thought was the perfect murder. While fleeing from the scene of the crime, he suffered a near-fatal accident that mangled his body beyond repair. An elderly scientist, Professor Vale, happened to come upon him and used his scientific skill to transfer Corben's brain into a robotic body covered by a flesh-like artificial skin. Corben discovered that his power source, a capsule of uranium, would only last a day, but was told by Vale that kryptonite would provide him an indefinite power supply.
After obtaining a job with the Daily Planet, Corben briefly tried to romance Lois Lane, while deciding that he would use his powers to eliminate Superman, the one person who might expose his criminal deeds. After setting a kryptonite death-trap for Superman, Corben stole what he thought was another sample of kryptonite from a museum as a new power supply, not knowing it was a fake prop; this mistake caused him to die, just as he was about to kill Lois Lane for discovering that he was not Superman (as he had pretended to be, being super-strong and invulnerable as a cyborg). Superman eventually escaped from the kryptonite trap and arrived just after Metallo (John Corben) had died. 
A second Metallo, John's brother Roger Corben, debuted in Superman #310 (April 1977) by Curt Swan and Martin Pasko. This Metallo was created by a secret organization named "SKULL" that transferred Roger's brain into a new robotic body so that he could get revenge on Superman for his brother's death. Like the previous Metallo, this one was also powered by kryptonite, although this newer version wore orange and green armor, as well as a green helmet to conceal the "new" identity he had created using plastic surgery (which turned out to be WGBS Staffer Martin Korda).
In this version, John Corben was a small-time con man who was fatally injured in a car crash, but thanks to luck, Professor Emmet Vale happened to pass by. Professor Vale was a pioneer in robotics and erroneously believed that Superman was the first in a wave of superpowered Kryptonian invaders after recovering Superman's ship and mistranslating Jor-El's message to his son. Vale transplanted Corben's brain into a robotic alloy body, which was powered by a two-pound chunk of kryptonite, and instructed him to kill Superman. Metallo, now Corben's new moniker, thanked Vale by snapping his neck and killing him.
Despite ignoring Vale's commands, Metallo came into conflict with Superman on various occasions, largely due to his continued activities as a petty thug. Metallo later lost his kryptonite heart to Lex Luthor, though back-up life support systems allowed him to reactivate himself and escape. He remained a thorn in Superman's side and was powerful enough to cripple the Doom Patrol. Still, the Indian-born hero who called herself Celsius did blow him apart with her thermal powers. Metallo later received a major upgrade via an unholy bargain with the demon Neron. As a result, Metallo could morph his body into any mechanical shape he could imagine (turning his hands into guns or "growing" a jet-pack from his back) and project his consciousness into any technological or metallic device. He could also grow to monstrous size. During one battle, his gigantic fists were separated and later turned into housing by other superheroes. In another incident, Metallo was rendered more insane by the Joker and used his height to destroy an elevated train of commuters.
As Superman and others learned on various occasions, the most effective way to neutralize Metallo was to remove his (largely invulnerable) head and isolate it from other metallic items.
In the 2009-10 miniseries Superman: Secret Origin, (which retells the origins of Superman and his supporting cast), Metallo is Sgt. John Corben. He serves under Lois Lane's father, General Sam Lane. General Lane is trying to push his daughter, Lois into a relationship with Corben. Though they had one date, she does not return his feelings for her. Corben is next seen signing up for a military option to neutralize Superman (ostensibly with the help of a powersuit built by LexCorp). However, in his first encounter with Superman, a stray bullet hit the Kryptonite rock inside the suit, leading to a disastrous energy cascade within the battlesuit which almost killed Corben. Through the efforts of Lex Luthor and a crack team of scientists, Corben survived, part-man, part-machine, with the Kryptonite rock functioning as his new heart. Driven by a hatred for this alien invader, he became the villain known as Metallo. Metallo, now wearing a green, orange and red armor, subsequently attacked Superman again in a rampage which endangered not only the citizens of Metropolis, but his own fellow soldiers. He was defeated by Superman once more.
In September 2011, The New 52 rebooted DC's continuity. In this new timeline, John Corben is under the command of General Sam Lane. General Lane tells him to talk to Lois Lane, when she keeps questioning where Superman is. It is implied that Corben and Lois once had a relationship. When Superman escapes from the military's custody, Corben is seen enlisting in what appears to be a military project co-opted by Lex Luthor, General Lane, and young scientist Doctor John Henry Irons – "Project Steel Soldier" – to go against Superman. Corben is seen in the "Metal 0" suit with scientists, mostly Irons, trying to help him. He continues believing that he did it for the affection of Lois and when the robotic needles are in his head, Metallo takes control and his heart bursts. Metallo then screams "Where is Superman?" Although the attack on Superman succeeds, Metallo is revealed to have been subverted by Brainiac as part of his own plans, and his rampage is defeated when Doctor Irons uses an armoured suit of his own to fight Corben and upload a computer virus that he designed in the event of such a situation. After escaping, and still under Brainiac's control, Corben continued to fight Superman until he was able to reason with Metallo and to fight Brainiac's influence because of his feelings for Lois Lane. In doing so, Corben attacked Brainiac until Superman could defeat the villain, but he subsequently fell into a coma and was taken back by the army.
It was revealed that the armor was keeping him alive thanks to alien technology, but without a heart he would soon die. General Lane told his scientists to find a way to save him since he helped to save Metropolis. He was later given a kryptonite heart to keep him alive since it was the only energy compatible with his cybernetics. After 31 months in a vegetative state, Corben was brought back with a shard of kryptonite to active duty in the U.S. Army. Since his actions caused the deaths of hundreds of civilians, General Lane tried to kill him by exploding the plane he was being carried in. He survived and sought vengeance against Lane at his base, only to be confronted by an upgraded soldier like himself "Metal-2.0". When Corben proves too much, Metal-2.0 activates his self-destruct mechanism, hoping to destroy Corben along with himself. However, he is saved by the Scarecrow and offered a place in the Secret Society of Super Villains, now calling himself Metallo. In "Forever Evil", Ultraman rips off his kryptonite heart, because of his addiction to the mineral.
Corben was eventually seen again incarcerated in John Henry's isolated super-prison, eventually drafted by the U.S. Government again shortly afterwards, but is only brought back into their service by compunction from Lois once more (who was secretly under Brainiac's influence). Given the present danger he represents as Doomsday was taking him over, Lois convinced Metallo to run Superman down in a kryptonite bombing run and was summarily incinerated by the blast; all that was left of him being the Metal Zero exo-mantel fused to his now-charred remains. Lois, now completely subsumed by the Brainiac consciousness inside of her, is able to recreate Corben's essential self by downloading her memory of the man he was into what was left of his old Metal-0 suit, said facsimile of the now-deceased military sergeant a loyal echo of whom he once was, obedient to her every whim. He would serve as her bodyguard as Dox's influence compelled her to cripple military defense systems around the world. He would immediately switch sides once Lois is freed from his control, however, and aid her in combating the alien threat to their world. As Superman and Lois departed to stop Brainiac, Metallo was left on Earth to defend Metropolis in their stead. After the crisis is resolved, Corben is later seen standing guard over Metropolis with Krypto, seemingly contented with his current position.
In the wake of Superman's identity being outed to the world as the hero began losing his powers, many an investigation was undertaken into his identity, contacts and motives by collective interests. Seeing as her life was in more danger than ever before, Metallo stuck close to his love as she went and did some investigating of her own in the meantime. While Vandal Savage made his play for ultimate power, Lois and Metallo were close by on the scene where Superman kept his warship from crushing a small town. While aiding Superman, as Lois refused to leave his side during the battle with Savage's empowered progeny, John's bionic shell was badly damaged. Looking to make good with all the bad in his life, he willingly offered his kryptonite heart to Superman (the depowered hero having discovered a treatment for his loss of powers that essentially involved giving himself chemotherapy with kryptonite), knowing full well that he could not survive without it.
Metallo’s metallic body offers him a high degree of protection from physical and energy attacks. He has enhanced abilities and no longer needs to eat, sleep, or breathe. His brain is hermetically sealed inside a shielded alloy skull that has its own power supply. When he was first created, he was powered by a kryptonite heart; losing that, he subsisted on plutonium instead. Additionally, because of his cyborg body, Metallo possesses superhuman strength and speed, enough to pose a challenge and even a threat to opponents such as Superman (in that case, he also takes advantage of the weakening power of kryptonite besides his own strength).
Over the course of his criminal career Metallo's body would be decimated constantly by various circumstances. As such he would receive numerous upgrades or whole new chassis' to replace his damaged parts, such as by the obscure supervillain organization Cerberus, which modified him with a vastly superior body, one with lead-lined skull-plating and an anatonic layer that even Superman could not demolish. This gave him greatly enhanced strength and durability, coupled with moderate mechanical regeneration to repair internal damage. He was later outfitted with a larger LexCorp tech body, which gave him laser vision and further augmented his physical abilities. Soon after it was destroyed, Corben had received a new body from fellow Kryptonite-powered supervillain Conduit; which gave Metallo radioactive blasts from his hands and could utilize geomagnetism to make him physically immovable, even by the Man of Steel, so long as he stood on solid ground or flooring within a building complex.
Metallo would eventually sell his soul (or what was left of it) to the archdemon Neron in return for increased power, gaining the abilities to mentally control and absorb any mechanical or metal object he focuses on and transforming any technology (himself included) into an extension of his exo-skeleton (an ability similar to the Cyborg Superman).
In experimenting with his newfound abilities, Metallo found he could alternate differing energy frequencies for harnessing and redistributing it from various power sources. Brainiac 13 upgraded Metallo to tap into various light spectra to better utilize his kryptonite-charged abilities. His mechanical body was also upgraded to be able to grow towards monolithic proportions. He is also occasionally portrayed as having a liquid metal-based endoskeleton, possessing the ability to morph parts of his body, specifically his limbs, into different weapons or tools, such as chainsaws, shovels, hammers, etc. While not a genius like Lex Luthor or Brainiac, Corben's time spent with machines has given him a gifted understanding of how they work, enabling him to tinker with their mechanical functions even before gaining his technomorphing capabilities.
During the publishing of Salvation Run it is revealed Metallo also boasts a high-calculus cyber-mind with which to run the numbers of possible and probable outcomes and success scenarios through. In the previous continuity, the Pre-Flashpoint Lex Luthor modified Corben to holster and utilize different forms of kryptonite; boasting mutagenic red-k, inverted blue-k and lastly, artificial depowering gold-k on top of the green-k he already possessed. He could even power a great many anti-Kryptonian armaments developed by Luthor through it.
His DC Universe Classics figure is a Collect and Connect figure in Wave 5 featuring the Riddler (Head & Torso), The Atom (right arm), The Eradicator (left arm), Amazo (right leg), and Black Lightning (left leg).
Asad Ullah Khan is an Indian microbiologist, biochemist and a professor at the Interdisciplinary Biotechnology Unit of the Aligarh Muslim University. He is known for his studies on multidrug resistant clinical strains as well as for the first sighting in India of Aligarh super bug (NDM-4), a variant of New Delhi metallo-beta-lactamase 1 (NDM-1). He is an elected fellow of the Royal Society of Chemistry, the Biotech Research Society, India and the Indian Academy of Microbiological Sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2012.Avibactam
Avibactam is a non-β-lactam β-lactamase inhibitor developed by Actavis (now Teva) jointly with AstraZeneca. A new drug application for avibactam in combination with ceftazidime (branded as Avycaz) was approved by the FDA on February 25, 2015, for treating complicated urinary tract (cUTI) and complicated intra-abdominal infections (cIAI) caused by antibiotic resistant-pathogens, including those caused by multi-drug resistant Gram-negative bacterial pathogens.Increasing resistance to cephalosporins among Gram-(−) bacterial pathogens, especially among hospital-acquired infections, results in part from the production of β-lactamase enzymes that deactivate these antibiotics. While the co-administration of a β-lactamase inhibitor can restore antibacterial activity to the cephalosporin, previously approved β-lactamase inhibitors such as tazobactam and clavulanic acid do not inhibit important classes of β-lactamases, including Klebsiella pneumoniae carbapenemases (KPCs), New Delhi metallo-β-lactamase 1 (NDM-1), and AmpC-type β-lactamases. Whilst avibactam inhibits class A (KPCs, CTX-M, TEM, SHV), class C (AmpC), and, some, class D serine β-lactamases (such as OXA-23, OXA-48), it has been reported to be a poor substrate/weak inhibitor of class B metallo-β-lactamases, such as VIM-2, VIM-4, SPM-1, BcII, NDM-1, Fez-1.Beta-lactamase
Beta-lactamases are enzymes (EC 188.8.131.52) produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties.
Beta-lactam antibiotics are typically used to treat a broad spectrum of Gram-positive and Gram-negative bacteria.
Beta-lactamases produced by Gram-negative organisms are usually secreted, especially when antibiotics are present in the environment.Betaine—homocysteine S-methyltransferase
In the field of enzymology, a betaine-homocysteine S-methyltransferase also known as betaine-homocysteine methyltransferase (BHMT) is a zinc metallo-enzyme that catalyzes the transfer of a methyl group from trimethylglycine and a hydrogen ion from homocysteine to produce dimethylglycine and methionine respectively:
Trimethylglycine (methyl donor) + homocysteine (hydrogen donor) → dimethylglycine (hydrogen receiver) + methionine (methyl receiver)
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. This enzyme participates in the metabolism of glycine, serine, threonine and also methionine.Bluvertigo
Bluvertigo were an Italian alternative rock band from the Milan metropolitan area. Originally formed in 1992 with the name "Golden Age", the band switched to the name Bluvertigo shortly before recording their first album. The founding members are Morgan (Marco Castoldi), Andy (Andrea Fumagalli) and Marco Pancaldi. Drummer Sergio Carnevale joined the band in 1994 while Pancaldi was replaced by Livio Magnini in 1996.
Bluvertigo's first album, Acidi e basi ("Acids and Bases"), was released in 1995. It was followed by Metallo non metallo ("Metal Nonmetal") in 1997 and Zero in 1999. These first three albums were later called "la trilogia chimica" ("the chemical trilogy") because every title has a reference to chemistry and the initial letters (AB-MN-Z) are respectively the first, the central and the last ones of the alphabet. In 2001 Bluvertigo participated to the Sanremo Music Festival with "L'assenzio (The Power of Nothing)". Following the release of the greatest hits album Pop Tools, the band went on hiatus for almost a decade. In 2008 they reunited for a live performance on MTV, an event later documented in the album MTV Storytellers (2008).
In 2003 Morgan released his first solo album: Le canzoni dell'appartamento.Cesare Bonizzi
Father Cesare Bonizzi, O.F.M. Cap. (born 15 March 1946), also known as Frate Cesare and Fratello Metallo ("Brother Metal") - which was also the name of his band, is an Italian Capuchin friar, who was known as a heavy metal singer.List of Amalgam Comics characters
The following is a list of fictional characters that appear in the comic books of Amalgam Comics. Any characters mentioned, but not seen, are excluded. They are listed by comic book and a team section is also provided. The amalgamations of characters or the Amalgam versions of one character are given. Plots of the Amalgam comic books are given in the list of Amalgam Comics publications and additional information about characters is provided in the references.MMP8
Neutrophil collagenase, also known as matrix metalloproteinase-8 (MMP-8) or PMNL collagenase (MNL-CL), is a collagen cleaving enzyme which is present in the connective tissue of most mammals. In humans, the MMP-8 protein is encoded by the MMP8 gene.Metallo-Chimique
Metallo-Chimique International N.V., based in Beerse, Belgium, also described simply as Metallo, is a privately held metals and mining company.l) The company was incorporated in 1919. Metallo now specializes in the recycling and refining of metalliferous materials (e.g. copper, tin, lead, zinc, as well as cable, waste from the electronics sector, car catalysts, and the like), to produce pure tin and lead, electrolytic copper, copper anodes and solder from a wide variety of scrap and residues.The company produces approximately 10,000 tons of cu-anodes, 1,500 tons of lead-ingots and 800 tons of tin-ingots per month. It is the leading producer of pure tin in Europe. All Metallo-Chimique final products are made out of scrap and by-products. The company buys and processes a wide range of different scrap grades and qualities including complex materials such as ashes, slags, oxides, and sludges. Due to this what it describes as "this unique situation", Metallo-Chimique sources its raw materials from all over the world.Metallo-beta-lactamase protein fold
The metallo-beta-lactamase protein fold is a protein domain contained in class B beta-lactamases and a number of other proteins.
These proteins include thiolesterases, members of the glyoxalase II family, that catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.
Metallo-beta-lactamases are important enzymes because they are involved in the breakdown of antibiotics by antibiotic-resistant bacteria. It is unclear whether metallo-beta-lactamase activity evolved once or twice within the superfamily; if twice, this would suggest structural exaptation.Neprilysin
Neprilysin (), also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10), and common acute lymphoblastic leukemia antigen (CALLA) is an enzyme that in humans is encoded by the MME gene. Neprilysin is a zinc-dependent metalloprotease that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. It also degrades the amyloid beta peptide whose abnormal folding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface.
Neprilysin is expressed in a wide variety of tissues and is particularly abundant in kidney. It is also a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.Hematopoetic progenitors expressing CD10 are considered "common lymphoid progenitors", which means they can differentiate into T, B or natural killer cells. CD10 is of use in hematological diagnosis since it is expressed by early B, pro-B and pre-B lymphocytes, and by lymph node germinal centers. Hematologic diseases in which it is positive include ALL, angioimmunoblastic T cell lymphoma, Burkitt lymphoma, chronic myelogenous leukemia in blast crisis (90%), diffuse large B-cell lymphoma (variable), follicular center cells (70%), hairy cell leukemia (10%), and myeloma (some). It tends to be negative in acute myeloid leukemia, chronic lymphocytic leukemia, mantle cell lymphoma, and marginal zone lymphoma. CD10 is found on non-T ALL cells, which derive from pre-B lymphocytes, and in germinal center-related non-Hodgkin lymphoma such as Burkitt lymphoma and follicular lymphoma, but not on leukemia cells or lymphomas, which originate in more mature B cells.New Delhi metallo-beta-lactamase 1
New Delhi metallo-beta-lactamase 1 (NDM-1) is an enzyme that makes bacteria resistant to a broad range of beta-lactam antibiotics. These include the antibiotics of the carbapenem family, which are a mainstay for the treatment of antibiotic-resistant bacterial infections. The gene for NDM-1 is one member of a large gene family that encodes beta-lactamase enzymes called carbapenemases. Bacteria that produce carbapenemases are often referred to in the news media as "superbugs" because infections caused by them are difficult to treat. Such bacteria are usually susceptible only to polymyxins and tigecycline.NDM-1 was first detected in a Klebsiella pneumoniae isolate from a Swedish patient of Indian origin in 2008. It was later detected in bacteria in India, Pakistan, the United Kingdom, the United States, Canada, and Japan.The most common bacteria that make this enzyme are gram-negative such as Escherichia coli and Klebsiella pneumoniae, but the gene for NDM-1 can spread from one strain of bacteria to another by horizontal gene transfer.Photodynamic therapy
Photodynamic therapy (PDT), is a form of phototherapy involving light and a photosensitizing chemical substance, used in conjunction with molecular oxygen to elicit cell death (phototoxicity). PDT has proven ability to kill microbial cells, including bacteria, fungi and viruses.
PDT is popularly used in treating acne. It is used clinically to treat a wide range of medical conditions, including wet age-related macular degeneration, psoriasis, atherosclerosis and has shown some efficacy in anti-viral treatments, including herpes. It also treats malignant cancers including head and neck, lung, bladder and particular skin.
The technology has also been tested for treatment of prostate cancer, both in a dog model and in human prostate cancer patients.It is recognised as a treatment strategy that is both minimally invasive and minimally toxic. Other light-based and laser therapies such as laser wound healing and rejuvenation, or intense pulsed light hair removal do not require a photosensitizer. Photosensitisers have been employed to sterilise blood plasma and water in order to remove blood-borne viruses and microbes and have been considered for agricultural uses, including herbicides and insecticides.Photodynamic therapy's advantages lessen the need for delicate surgery and lengthy recuperation and minimal formation of scar tissue and disfigurement. A side effect is the associated photosensitisation of skin tissue.Superman Returns (video game)
Superman Returns is a video game based on the film of the same name, It was developed by EA Tiburon and published by Electronic Arts in conjunction with Warner Bros. Interactive Entertainment and DC Comics.
In the game, Superman combats Bizarro, as well as other classic villains (including Metallo, Mongul, and Riot) as well as being able to play as Bizarro in one of the minigames. It was produced for the Xbox 360 as well as the PlayStation 2 and Nintendo DS. A port for the PlayStation Portable was planned but cancelled due to it not having enough power to support the game.
The game features the voice and likeness of Brandon Routh (Superman/Clark Kent) as well as the voices of Kevin Spacey (Lex Luthor), Kate Bosworth (Lois Lane), Parker Posey (Kitty Kowalski) and Sam Huntington (Jimmy Olsen), all reprising their roles from the Warner Bros. Pictures film directed by Bryan Singer.
The Nintendo DS version also features games based on the film, but they are fundamentally different from the console title. The games were delayed from their original release date (set to coincide with the theatrical release of the film) due to design complications and issues with polish on the console game. The handheld games were delayed in order to preserve a simultaneous release with non-handheld SKUs. The games were ultimately released on November 22, 2006 in the United States and November 30 in Australia, to coincide with the DVD release of Superman Returns.Superman Revenge Squad
The Superman Revenge Squad is the name of two fictional organizations in the DC Comics universe. As their name suggests, they are enemies of Superman.
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