Lutetium

Lutetium is a chemical element with symbol Lu and atomic number 71. It is a silvery white metal, which resists corrosion in dry air, but not in moist air. Lutetium is the last element in the lanthanide series, and it is traditionally counted among the rare earths. Lutetium is sometimes considered the first element of the 6th-period transition metals, although lanthanum is more often considered as such.

Lutetium was independently discovered in 1907 by French scientist Georges Urbain, Austrian mineralogist Baron Carl Auer von Welsbach, and American chemist Charles James. All of these researchers found lutetium as an impurity in the mineral ytterbia, which was previously thought to consist entirely of ytterbium. The dispute on the priority of the discovery occurred shortly after, with Urbain and Welsbach accusing each other of publishing results influenced by the published research of the other; the naming honor went to Urbain, as he had published his results earlier. He chose the name lutecium for the new element, but in 1949 the spelling of element 71 was changed to lutetium. In 1909, the priority was finally granted to Urbain and his names were adopted as official ones; however, the name cassiopeium (or later cassiopium) for element 71 proposed by Welsbach was used by many German scientists until the 1950s.

Lutetium is not a particularly abundant element, although it is significantly more common than silver in the earth's crust. It has few specific uses. Lutetium-176 is a relatively abundant (2.5%) radioactive isotope with a half-life of about 38 billion years, used to determine the age of minerals and meteorites. Lutetium usually occurs in association with the element yttrium and is sometimes used in metal alloys and as a catalyst in various chemical reactions. 177Lu-DOTA-TATE is used for radionuclide therapy (see Nuclear medicine) on neuroendocrine tumours. Lutetium has the highest Brinell hardness of any lanthanide, at 890–1300 MPa.[3]

Lutetium,  71Lu
Lutetium sublimed dendritic and 1cm3 cube
Lutetium
Pronunciation/ljuːˈtiːʃiəm/ (lew-TEE-shee-əm)
Appearancesilvery white
Standard atomic weight Ar, std(Lu)174.9668(1)[1]
Lutetium in the periodic table
Hydrogen Helium
Lithium Beryllium Boron Carbon Nitrogen Oxygen Fluorine Neon
Sodium Magnesium Aluminium Silicon Phosphorus Sulfur Chlorine Argon
Potassium Calcium Scandium Titanium Vanadium Chromium Manganese Iron Cobalt Nickel Copper Zinc Gallium Germanium Arsenic Selenium Bromine Krypton
Rubidium Strontium Yttrium Zirconium Niobium Molybdenum Technetium Ruthenium Rhodium Palladium Silver Cadmium Indium Tin Antimony Tellurium Iodine Xenon
Caesium Barium Lanthanum Cerium Praseodymium Neodymium Promethium Samarium Europium Gadolinium Terbium Dysprosium Holmium Erbium Thulium Ytterbium Lutetium Hafnium Tantalum Tungsten Rhenium Osmium Iridium Platinum Gold Mercury (element) Thallium Lead Bismuth Polonium Astatine Radon
Francium Radium Actinium Thorium Protactinium Uranium Neptunium Plutonium Americium Curium Berkelium Californium Einsteinium Fermium Mendelevium Nobelium Lawrencium Rutherfordium Dubnium Seaborgium Bohrium Hassium Meitnerium Darmstadtium Roentgenium Copernicium Nihonium Flerovium Moscovium Livermorium Tennessine Oganesson


Lu

Lr
ytterbiumlutetiumhafnium
Atomic number (Z)71
Groupgroup n/a
Periodperiod 6
Blockf-block
Element category  lanthanide, sometimes considered a transition metal
Electron configuration[Xe] 4f14 5d1 6s2
Electrons per shell
2, 8, 18, 32, 9, 2
Physical properties
Phase at STPsolid
Melting point1925 K ​(1652 °C, ​3006 °F)
Boiling point3675 K ​(3402 °C, ​6156 °F)
Density (near r.t.)9.841 g/cm3
when liquid (at m.p.)9.3 g/cm3
Heat of fusionca. 22 kJ/mol
Heat of vaporization414 kJ/mol
Molar heat capacity26.86 J/(mol·K)
Vapor pressure
P (Pa) 1 10 100 1 k 10 k 100 k
at T (K) 1906 2103 2346 (2653) (3072) (3663)
Atomic properties
Oxidation states+1, +2, +3 (a weakly basic oxide)
ElectronegativityPauling scale: 1.27
Ionization energies
  • 1st: 523.5 kJ/mol
  • 2nd: 1340 kJ/mol
  • 3rd: 2022.3 kJ/mol
Atomic radiusempirical: 174 pm
Covalent radius187±8 pm
Color lines in a spectral range
Spectral lines of lutetium
Other properties
Natural occurrenceprimordial
Crystal structurehexagonal close-packed (hcp)
Hexagonal close packed crystal structure for lutetium
Thermal expansionpoly: 9.9 µm/(m·K) (at r.t.)
Thermal conductivity16.4 W/(m·K)
Electrical resistivitypoly: 582 nΩ·m (at r.t.)
Magnetic orderingparamagnetic[2]
Young's modulus68.6 GPa
Shear modulus27.2 GPa
Bulk modulus47.6 GPa
Poisson ratio0.261
Vickers hardness755–1160 MPa
Brinell hardness890–1300 MPa
CAS Number7439-94-3
History
Namingafter Lutetia, Latin for: Paris, in the Roman era
DiscoveryCarl Auer von Welsbach and Georges Urbain (1906)
First isolationCarl Auer von Welsbach (1906)
Named byGeorges Urbain (1906)
Main isotopes of lutetium
Iso­tope Abun­dance Half-life (t1/2) Decay mode Pro­duct
173Lu syn 1.37 y ε 173Yb
174Lu syn 3.31 y ε 174Yb
175Lu 97.401% stable
176Lu 2.599% 3.78×1010 y β 176Hf

Characteristics

Physical properties

A lutetium atom has 71 electrons, arranged in the configuration [Xe] 4f145d16s2.[4] When entering a chemical reaction, the atom loses its two outermost electrons and the single 5d-electron. The lutetium atom is the smallest among the lanthanide atoms, due to the lanthanide contraction,[5] and as a result lutetium has the highest density, melting point, and hardness of the lanthanides.[6]

Chemical properties and compounds

Lutetium's compounds always contain the element in the oxidation state +3. Aqueous solutions of most lutetium salts are colorless and form white crystalline solids upon drying, with the common exception of the iodide. The soluble salts, such as nitrate, sulfate and acetate form hydrates upon crystallization. The oxide, hydroxide, fluoride, carbonate, phosphate and oxalate are insoluble in water.[7]

Lutetium metal is slightly unstable in air at standard conditions, but it burns readily at 150 °C to form lutetium oxide. The resulting compound is known to absorb water and carbon dioxide, and may be used to remove vapors of these compounds from closed atmospheres.[8] Similar observations are made during reaction between lutetium and water (slow when cold and fast when hot); lutetium hydroxide is formed in the reaction.[9] Lutetium metal is known to react with the four lightest halogens to form trihalides; all of them (except the fluoride) are soluble in water.

Lutetium dissolves readily in weak acids[8] and dilute sulfuric acid to form solutions containing the colorless lutetium ions, which are coordinated by between seven and nine water molecules, the average being [Lu(H2O)8.2]3+.[10]

2 Lu + 3 H2SO4 → 2 Lu3+ + 3 SO2–
4
+ 3 H2

Isotopes

Lutetium occurs on the Earth in form of two isotopes: lutetium-175 and lutetium-176. Out of these two, only the former is stable, making the element monoisotopic. The latter one, lutetium-176, decays via beta decay with a half-life of 3.78×1010 years; it makes up about 2.5% of natural lutetium.[11] To date, 32 synthetic radioisotopes of the element have been characterized, ranging in mass from 149.973 (lutetium-150) to 183.961 (lutetium-184); the most stable such isotopes are lutetium-174 with a half-life of 3.31 years, and lutetium-173 with a half-life of 1.37 years.[11] All of the remaining radioactive isotopes have half-lives that are less than 9 days, and the majority of these have half-lives that are less than half an hour.[11] Isotopes lighter than the stable lutetium-175 decay via electron capture (to produce isotopes of ytterbium), with some alpha and positron emission; the heavier isotopes decay primarily via beta decay, producing hafnium isotopes.[11]

The element also has 42 nuclear isomers, with masses of 150, 151, 153–162, 166–180 (not every mass number corresponds to only one isomer). The most stable of them are lutetium-177m, with half-life of 160.4 days and lutetium-174m, with half-life of 142 days; this is longer than half-lives of the ground states of all radioactive lutetium isotopes, except only for lutetium-173, 174, and 176.[11]

History

Lutetium, derived from the Latin Lutetia (Paris), was independently discovered in 1907 by French scientist Georges Urbain, Austrian mineralogist Baron Carl Auer von Welsbach, and American chemist Charles James.[12][13] They found it as an impurity in ytterbia, which was thought by Swiss chemist Jean Charles Galissard de Marignac to consist entirely of ytterbium.[14] The scientists proposed different names for the elements: Urbain chose neoytterbium and lutecium,[15] whereas Welsbach chose aldebaranium and cassiopeium (after Aldebaran and Cassiopeia).[16] Both of these articles accused the other man of publishing results based on those of the author.

The International Commission on Atomic Weights, which was then responsible for the attribution of new element names, settled the dispute in 1909 by granting priority to Urbain and adopting his names as official ones, based on the fact that the separation of lutetium from Marignac's ytterbium was first described by Urbain;[14] after Urbain's names were recognized, neoytterbium was reverted to ytterbium. Until the 1950s, some German-speaking chemists called lutetium by Welsbach's name, cassiopeium; in 1949, the spelling of element 71 was changed to lutetium. The reason for this was that Welsbach's 1907 samples of lutetium had been pure, while Urbain's 1907 samples only contained traces of lutetium.[17] This later misled Urbain into thinking that he had discovered element 72, which he named celtium, which was actually very pure lutetium. The later discrediting of Urbain's work on element 72 led to a reappraisal of Welsbach's work on element 71, so that the element was renamed to cassiopeium in German-speaking countries for some time.[17] Charles James, who stayed out of the priority argument, worked on a much larger scale and possessed the largest supply of lutetium at the time.[18] Pure lutetium metal was first produced in 1953.[18]

Occurrence and production

Monazit - Mosambik, O-Afrika
Monazite

Found with almost all other rare-earth metals but never by itself, lutetium is very difficult to separate from other elements. Its principal commercial source is as a by-product from the processing of the rare earth phosphate mineral monazite (Ce,La,...)PO4, which has concentrations of only 0.0001% of the element,[8] not much higher than the abundance of lutetium in the Earth crust of about 0.5 mg/kg. No lutetium-dominant minerals are currently known.[19] The main mining areas are China, United States, Brazil, India, Sri Lanka and Australia. The world production of lutetium (in the form of oxide) is about 10 tonnes per year.[18] Pure lutetium metal is very difficult to prepare. It is one of the rarest and most expensive of the rare earth metals with the price about US$10,000 per kilogram, or about one-fourth that of gold.[20][21]

Crushed minerals are treated with hot concentrated sulfuric acid to produce water-soluble sulfates of rare earths. Thorium precipitates out of solution as hydroxide and is removed. After that the solution is treated with ammonium oxalate to convert rare earths into their insoluble oxalates. The oxalates are converted to oxides by annealing. The oxides are dissolved in nitric acid that excludes one of the main components, cerium, whose oxide is insoluble in HNO3. Several rare earth metals, including lutetium, are separated as a double salt with ammonium nitrate by crystallization. Lutetium is separated by ion exchange. In this process, rare-earth ions are sorbed onto suitable ion-exchange resin by exchange with hydrogen, ammonium or cupric ions present in the resin. Lutetium salts are then selectively washed out by suitable complexing agent. Lutetium metal is then obtained by reduction of anhydrous LuCl3 or LuF3 by either an alkali metal or alkaline earth metal.[7]

2 LuCl3 + 3 Ca → 2 Lu + 3 CaCl2

Applications

Because of production difficulty and high price, lutetium has very few commercial uses, especially since it is rarer than most of the other lanthanides but is chemically not very different. However, stable lutetium can be used as catalysts in petroleum cracking in refineries and can also be used in alkylation, hydrogenation, and polymerization applications.[22]

Lutetium aluminium garnet (Al5Lu3O12) has been proposed for use as a lens material in high refractive index immersion lithography.[23] Additionally, a tiny amount of lutetium is added as a dopant to gadolinium gallium garnet (GGG), which is used in magnetic bubble memory devices.[24] Cerium-doped lutetium oxyorthosilicate (LSO) is currently the preferred compound for detectors in positron emission tomography (PET).[25][26] Lutetium aluminium garnet (LuAG) is used as a phosphor in LED light bulbs.[27][28]

Aside from stable lutetium, its radioactive isotopes have several specific uses. The suitable half-life and decay mode made lutetium-176 used as a pure beta emitter, using lutetium which has been exposed to neutron activation, and in lutetium–hafnium dating to date meteorites.[29] The synthetic isotope lutetium-177 bound to octreotate (a somatostatin analogue), is used experimentally in targeted radionuclide therapy for neuroendocrine tumors.[30] Indeed, lutetium-177 is seeing increasing use as a radionuclide, in neuroendrocine tumor therapy and bone pain palliation.[31][32] Research indicates that lutetium-ion atomic clocks could provide greater accuracy than any existing atomic clock.[33]

Lutetium tantalate (LuTaO4) is the densest known stable white material (density 9.81 g/cm3)[34] and therefore is an ideal host for X-ray phosphors.[35][36] The only denser white material is thorium dioxide, with density of 10 g/cm3, but the thorium it contains is radioactive.

Precautions

Like other rare-earth metals, lutetium is regarded as having a low degree of toxicity, but its compounds should be handled with care nonetheless: for example, lutetium fluoride inhalation is dangerous and the compound irritates skin.[8] Lutetium nitrate may be dangerous as it may explode and burn once heated. Lutetium oxide powder is toxic as well if inhaled or ingested.[8]

Similarly to the other rare-earth metals, lutetium has no known biological role, but it is found even in humans, concentrating in bones, and to a lesser extent in the liver and kidneys.[18] Lutetium salts are known to occur together with other lanthanide salts in nature; the element is the least abundant in the human body of all lanthanides.[18] Human diets have not been monitored for lutetium content, so it is not known how much the average human takes in, but estimations show the amount is only about several micrograms per year, all coming from tiny amounts taken by plants. Soluble lutetium salts are mildly toxic, but insoluble ones are not.[18]

References

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DOTA-TATE

DOTA-TATE (Also known as DOTA-octreotate, oxodotreotide and DOTA-(Tyr3)-octreotate/ DOTA-0-Tyr3-Octreotate) is an amino acid peptide, with a covalently bonded DOTA bifunctional chelator.

DOTA-TATE can be bound with radionuclides such as gallium-68 and lutetium-177 to form radiopharmaceuticals for PET imaging or radionuclide therapy. 177Lu DOTA-TATE therapy is a form of peptide receptor radionuclide therapy (PRRT) which targets somatostatin receptors (SSR). In that form of application it is a form of targeted drug delivery.

Georges Urbain

Georges Urbain (12 April 1872 – 5 November 1938 in Paris) French chemist, professor of Sorbonne. He studied at the elite École supérieure de physique et de chimie industrielles de la ville de Paris (ESPCI ParisTech). He discovered the element lutetium (atomic number 71) independently in 1907-08.

Group 3 element

Group 3 is a group of elements in the periodic table. This group, like other d-block groups, should contain four elements, but it is not agreed what elements belong in the group. Scandium (Sc) and yttrium (Y) are always included, but the other two spaces are usually occupied by lanthanum (La) and actinium (Ac), or by lutetium (Lu) and lawrencium (Lr); less frequently, it is considered the group should be expanded to 32 elements (with all the lanthanides and actinides included) or contracted to contain only scandium and yttrium. When the group is understood to contain all of the lanthanides, its trivial name is the rare-earth metals.

Three group 3 elements occur naturally: scandium, yttrium, and either lanthanum or lutetium. Lanthanum continues the trend started by two lighter members in general chemical behavior, while lutetium behaves more similarly to yttrium. While the choice of lutetium would be in accordance with the trend for period 6 transition metals to behave more similarly to their upper periodic table neighbors, the choice of lanthanum is in accordance with the trends in the s-block, which the group 3 elements are chemically more similar to. They all are silvery-white metals under standard conditions. The fourth element, either actinium or lawrencium, has only radioactive isotopes. Actinium, which occurs only in trace amounts, continues the trend in chemical behavior for metals that form tripositive ions with a noble gas configuration; synthetic lawrencium is calculated and partially shown to be more similar to lutetium and yttrium. So far, no experiments have been conducted to synthesize any element that could be the next group 3 element. Unbiunium (Ubu), which could be considered a group 3 element if preceded by lanthanum and actinium, might be synthesized in the near future, it being only three spaces away from the current heaviest element known, oganesson.

Isotopes of lutetium

Naturally occurring lutetium (71Lu) is composed of 1 stable isotope 175Lu (97.41% natural abundance) and one long-lived radioisotope, 176Lu with a half-life of 3.78 × 1010 years (2.59% natural abundance). Thirty-four radioisotopes have been characterized, with the most stable, besides 176Lu, being 174Lu with a half-life of 3.31 years, and 173Lu with a half-life of 1.37 years. All of the remaining radioactive isotopes have half-lives that are less than 9 days, and the majority of these have half-lives that are less than half an hour. This element also has 18 meta states, with the most stable being 177mLu (t1/2 160.4 days), 174mLu (t1/2 142 days) and 178mLu (t1/2 23.1 minutes).

The isotopes of lutetium range in atomic weight from 149.973 (150Lu) to 183.961 (184Lu). The primary decay mode before the most abundant stable isotope, 175Lu, is electron capture (with some alpha and positron emission), and the primary mode after is beta emission. The primary decay products before 175Lu are isotopes of ytterbium and the primary products after are isotopes of hafnium.

Lanthanide

The lanthanide () or lanthanoid () series of chemical elements comprises the 15 metallic chemical elements with atomic numbers 57 through 71, from lanthanum through lutetium. These elements, along with the chemically similar elements scandium and yttrium, are often collectively known as the rare earth elements.

The informal chemical symbol Ln is used in general discussions of lanthanide chemistry to refer to any lanthanide. All but one of the lanthanides are f-block elements, corresponding to the filling of the 4f electron shell; depending on the source, either lanthanum or lutetium is considered a d-block element, but is included due to its chemical similarities with the other 14. All lanthanide elements form trivalent cations, Ln3+, whose chemistry is largely determined by the ionic radius, which decreases steadily from lanthanum to lutetium.

They are called lanthanides because the elements in the series are chemically similar to lanthanum. Both lanthanum and lutetium have been labeled as group 3 elements, because they have a single valence electron in the 5d shell. However, both elements are often included in discussions of the chemistry of lanthanide elements. Lanthanum is the more often omitted of the two, because its placement as a group 3 element is somewhat more common in texts and for semantic reasons: since "lanthanide" means "like lanthanum", it has been argued that lanthanum cannot logically be a lanthanide, but IUPAC acknowledges its inclusion based on common usage.In presentations of the periodic table, the lanthanides and the actinides are customarily shown as two additional rows below the main body of the table, with placeholders or else a selected single element of each series (either lanthanum and actinium, or lutetium and lawrencium) shown in a single cell of the main table, between barium and hafnium, and radium and rutherfordium, respectively. This convention is entirely a matter of aesthetics and formatting practicality; a rarely used wide-formatted periodic table inserts the lanthanide and actinide series in their proper places, as parts of the table's sixth and seventh rows (periods).

Lanthanide contraction

The lanthanide contraction is the greater-than-expected decrease in ionic radii of the elements in the lanthanide series from atomic number 57, lanthanum, to 71, lutetium, which results in smaller than otherwise expected ionic radii for the subsequent elements starting with 72, hafnium. The term was coined by the Norwegian geochemist Victor Goldschmidt in his series "Geochemische Verteilungsgesetze der Elemente".

Lanthanum

Lanthanum is a chemical element with symbol La and atomic number 57. It is a soft, ductile, silvery-white metal that tarnishes rapidly when exposed to air and is soft enough to be cut with a knife. It is the eponym of the lanthanide series, a group of 15 similar elements between lanthanum and lutetium in the periodic table, of which lanthanum is the first and the prototype. It is also sometimes considered the first element of the 6th-period transition metals, which would put it in group 3, although lutetium is sometimes placed in this position instead. Lanthanum is traditionally counted among the rare earth elements. The usual oxidation state is +3. Lanthanum has no biological role in humans but is essential to some bacteria. It is not particularly toxic to humans but does show some antimicrobial activity.

Lanthanum usually occurs together with cerium and the other rare earth elements. Lanthanum was first found by the Swedish chemist Carl Gustav Mosander in 1839 as an impurity in cerium nitrate – hence the name lanthanum, from the Ancient Greek λανθάνειν (lanthanein), meaning "to lie hidden". Although it is classified as a rare earth element, lanthanum is the 28th most abundant element in the Earth's crust, almost three times as abundant as lead. In minerals such as monazite and bastnäsite, lanthanum composes about a quarter of the lanthanide content. It is extracted from those minerals by a process of such complexity that pure lanthanum metal was not isolated until 1923.

Lanthanum compounds have numerous applications as catalysts, additives in glass, carbon arc lamps for studio lights and projectors, ignition elements in lighters and torches, electron cathodes, scintillators, GTAW electrodes, and other things. Lanthanum carbonate is used as a phosphate binder in cases of renal failure. It is also an element in the 6th period and in the 3rd group.

Lawrencium

Lawrencium is a synthetic chemical element with symbol Lr (formerly Lw) and atomic number 103. It is named in honor of Ernest Lawrence, inventor of the cyclotron, a device that was used to discover many artificial radioactive elements. A radioactive metal, lawrencium is the eleventh transuranic element and is also the final member of the actinide series. Like all elements with atomic number over 100, lawrencium can only be produced in particle accelerators by bombarding lighter elements with charged particles. Twelve isotopes of lawrencium are currently known; the most stable is 266Lr with a half-life of 11 hours, but the shorter-lived 260Lr (half-life 2.7 minutes) is most commonly used in chemistry because it can be produced on a larger scale.

Chemistry experiments have confirmed that lawrencium behaves as a heavier homolog to lutetium in the periodic table, and is a trivalent element. It thus could also be classified as the first of the 7th-period transition metals: however, its electron configuration is anomalous for its position in the periodic table, having an s2p configuration instead of the s2d configuration of its homolog lutetium. This means that lawrencium may be more volatile than expected for its position in the periodic table and have a volatility comparable to that of lead.

In the 1950s, 1960s, and 1970s, many claims of the synthesis of lawrencium of varying quality were made from laboratories in the Soviet Union and the United States. The priority of the discovery and therefore the naming of the element was disputed between Soviet and American scientists, and while the International Union of Pure and Applied Chemistry (IUPAC) initially established lawrencium as the official name for the element and gave the American team credit for the discovery, this was reevaluated in 1997, giving both teams shared credit for the discovery but not changing the element's name.

Lilotomab

Lilotomab (formerly tetulomab, HH1) is a murine monoclonal antibody against CD37, a glycoprotein which is expressed on the surface of mature human B cells. It was generated at the Norwegian Radium Hospital.As of 2016 it was under development by the Norwegian company Nordic Nanovector ASA as a radioimmunotherapeutic in which lilotomab is conjugated to the beta radiation-emitting isotope lutetium-177 by means of a linker called satetraxetan, a derivative of DOTA. This compound is called 177Lu-HH1 or lutetium (177Lu) lilotomab satetraxetan (trade name Betalutin). As of 2016, a phase 1/2 clinical trial in people with non-Hodgkin lymphoma was underway.

List of chemical elements naming controversies

The currently accepted names and symbols of the chemical elements are determined by the International Union of Pure and Applied Chemistry (IUPAC), usually following recommendations by the recognized discoverers of each element. However the names of several elements have been the subject of controversies until IUPAC established an official name. In most cases the controversy was due to a priority dispute as to who first found conclusive evidence for the existence of an element, or as to what evidence was in fact conclusive.

Lutetium(III) bromide

Lutetium(III) bromide is a crystalline compound made of one lutetium atom and three bromine atoms. It takes the form of a white powder at room temperature. It is hygroscopic. It is odorless.

Lutetium(III) chloride

Lutetium(III) chloride or lutetium trichloride is the chemical compound composed of lutetium and chlorine with the formula LuCl3. It forms hygroscopic white monoclinic crystals. Lutetium(III) chloride has the YCl3 (AlCl3) layer structure with octahedral lutetium ions.

Lutetium(III) oxide

Lutetium(III) oxide, a white solid, is a cubic compound of lutetium sometimes used in the preparation of specialty glasses. It is also called lutecia. It is a lanthanide oxide, also known as a rare earth.

Lutetium aluminium garnet

Lutetium aluminum garnet (commonly abbreviated LuAG, molecular formula Al5Lu3O12) is an inorganic compound with a unique crystal structure primarily known for its use in high-efficiency laser devices. LuAG is also useful in the synthesis of transparent ceramics.LuAG is a dopable scintillating crystal that will demonstrate luminescence after excitation. Scintillating crystals are selected for high structural perfection, high density and high effective atomic number. LuAG is particularly favored over other crystals for its high density and thermal conductivity. LuAG has a relatively small lattice constant in comparison to the other rare-earth garnets, which results in a higher density producing a crystal field with narrower linewidths and greater energy level splitting in absorption and emission. These properties make it an excellent host for active ions such as Yb, Tm, Er, and Ho employed in diode-pumped solid-state lasers. The density of the lutetium crystal is greater than that of other metals, such as yttrium, meaning that the crystal properties do not change with the addition of dopant ions. It can be especially useful for high energy particle detection and quatification on account of its density and thermal stability. This high melting temperature, in addition to the lack of availability of lutetium has made this crystal less commonly used than its fellow garnets, despite its favorable physical properties.

Lutetium tantalate

Lutetium tantalate is a chemical compound of lutetium, tantalum and oxygen with the formula LuTaO4. With a density of 9.81 g/cm3, it is the densest known white stable material. (Although thorium dioxide ThO2 is also white and has a higher density of 10 g/cm3, it is radioactively unstable; while not radioactive enough to make it unstable as a material, even its low rate of decay is still too much for certain uses such as phosphors for detecting ionising radiation.) The white color and high density of LuTaO4 make it ideal for phosphor applications, though the high cost of lutetium is a hindrance.

Lutetium–hafnium dating

Lutetium–hafnium dating is a geochronological dating method utilizing the radioactive decay system of lutetium–176 to hafnium–176. With a commonly accepted half-life of 37.1 billion years, the long-living Lu–Hf decay pair survives through geological time scales, thus is useful in geological studies. Due to chemical properties of the two elements, namely their valences and ionic radii, Lu is usually found in trace amount in rare-earth element loving minerals, such as garnet and phosphates, while Hf is usually found in trace amount in zirconium-rich minerals, such as zircon, baddeleyite and zirkelite.The trace concentration of the Lu and Hf in earth materials posed some technological difficulties in using Lu–Hf dating extensively in the 1980s. With the use of inductively coupled plasma mass spectrometry (ICP–MS) with multi-collector (also known as MC–ICP–MS) in later years, the dating method is made applicable to date diverse earth materials. The Lu–Hf system is now a common tool in geological studies such as igneous and metamorphic rock petrogenesis, early earth mantle-crust differentiation, and provenance.

Motexafin lutetium

Motexafin lutetium is a texaphyrin, marketed as Antrin by Pharmacyclics Inc.

It is a photosensitiser for use in photodynamic therapy to treat skin conditions and superficial cancers.

It has also been tested for use in photoangioplasty (photodynamic treatment of diseased arteries).It is photoactivated by 732 nm light which allows greater depth of penetration.

Periodic table

The periodic table, also known as the periodic table of elements, is a tabular display of the chemical elements, which are arranged by atomic number, electron configuration, and recurring chemical properties. The structure of the table shows periodic trends. The seven rows of the table, called periods, generally have metals on the left and non-metals on the right. The columns, called groups, contain elements with similar chemical behaviours. Six groups have accepted names as well as assigned numbers: for example, group 17 elements are the halogens; and group 18 are the noble gases. Also displayed are four simple rectangular areas or blocks associated with the filling of different atomic orbitals.

The organization of the periodic table can be used to derive relationships between the various element properties, and also to predict chemical properties and behaviours of undiscovered or newly synthesized elements. Russian chemist Dmitri Mendeleev published the first recognizable periodic table in 1869, developed mainly to illustrate periodic trends of the then-known elements. He also predicted some properties of unidentified elements that were expected to fill gaps within the table. Most of his forecasts proved to be correct. Mendeleev's idea has been slowly expanded and refined with the discovery or synthesis of further new elements and the development of new theoretical models to explain chemical behaviour. The modern periodic table now provides a useful framework for analyzing chemical reactions, and continues to be widely used in chemistry, nuclear physics and other sciences.

The elements from atomic numbers 1 (hydrogen) through 118 (oganesson) have been discovered or synthesized, completing seven full rows of the periodic table. The first 94 elements all occur naturally, though some are found only in trace amounts and a few were discovered in nature only after having first been synthesized. Elements 95 to 118 have only been synthesized in laboratories or nuclear reactors. The synthesis of elements having higher atomic numbers is currently being pursued: these elements would begin an eighth row, and theoretical work has been done to suggest possible candidates for this extension. Numerous synthetic radionuclides of naturally occurring elements have also been produced in laboratories.

Ytterbium

Ytterbium is a chemical element with symbol Yb and atomic number 70. It is the fourteenth and penultimate element in the lanthanide series, which is the basis of the relative stability of its +2 oxidation state. However, like the other lanthanides, its most common oxidation state is +3, as in its oxide, halides, and other compounds. In aqueous solution, like compounds of other late lanthanides, soluble ytterbium compounds form complexes with nine water molecules. Because of its closed-shell electron configuration, its density and melting and boiling points differ significantly from those of most other lanthanides.

In 1878, the Swiss chemist Jean Charles Galissard de Marignac separated from the rare earth "erbia" another independent component, which he called "ytterbia", for Ytterby, the village in Sweden near where he found the new component of erbium. He suspected that ytterbia was a compound of a new element that he called "ytterbium" (in total, four elements were named after the village, the others being yttrium, terbium and erbium). In 1907, the new earth "lutecia" was separated from ytterbia, from which the element "lutecium" (now lutetium) was extracted by Georges Urbain, Carl Auer von Welsbach, and Charles James. After some discussion, Marignac's name "ytterbium" was retained. A relatively pure sample of the metal was not obtained until 1953. At present, ytterbium is mainly used as a dopant of stainless steel or active laser media, and less often as a gamma ray source.

Natural ytterbium is a mixture of seven stable isotopes, which altogether are present at concentrations of 3 parts per million. This element is mined in China, the United States, Brazil, and India in form of the minerals monazite, euxenite, and xenotime. The ytterbium concentration is low because it is found only among many other rare earth elements; moreover, it is among the least abundant. Once extracted and prepared, ytterbium is somewhat hazardous as an eye and skin irritant. The metal is a fire and explosion hazard.

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