Formaldehyde (systematic name methanal) is a naturally occurring organic compound with the formula CH2O (H-CHO). It is the simplest of the aldehydes (R-CHO). The common name of this substance comes from its similarity and relation to formic acid.
Formaldehyde is an important precursor to many other materials and chemical compounds. In 1996, the installed capacity for the production of formaldehyde was estimated at 8.7 million tons per year. It is mainly used in the production of industrial resins, e.g., for particle board and coatings.
In view of its widespread use, toxicity, and volatility, formaldehyde poses a significant danger to human health. In 2011, the US National Toxicology Program described formaldehyde as "known to be a human carcinogen".
|Preferred IUPAC name
|Systematic IUPAC name
Formalin (aqueous solution)
3D model (JSmol)
|E number||E240 (preservatives)|
|Molar mass||30.026 g·mol−1|
|Density||0.8153 g/cm3 (−20 °C)|
|Melting point||−92 °C (−134 °F; 181 K)|
|Boiling point||−19 °C (−2 °F; 254 K)|
|400 g L−1|
|Vapor pressure||< 1 atm|
|Acidity (pKa)||13.27 (hydrate) |
|Safety data sheet||MSDS|
|GHS signal word||DANGER|
|H301, H311, H331, H314, H317, H335, H336, H341, H350, H370|
|P201, P280, P303+361+353, P304+340, P309+311, P305+351+338|
|Flash point||64 °C (147 °F; 337 K)|
|430 °C (806 °F; 703 K)|
|Lethal dose or concentration (LD, LC):|
LD50 (median dose)
|100 mg/kg (oral, rat)|
LC50 (median concentration)
|333 ppm (mouse, 2 hr)|
815 ppm (rat, 30 min)
LCLo (lowest published)
|333 ppm (cat, 2 hr)|
|US health exposure limits (NIOSH):|
|TWA 0.75 ppm ST 2 ppm (as formaldehyde and formalin)|
|Ca TWA 0.016 ppm C 0.1 ppm [15-minute]|
IDLH (Immediate danger)
|Ca [20 ppm]|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Formaldehyde is more complicated than many simple carbon compounds in that it adopts several different forms. As a gas, formaldehyde is colorless and has a characteristic pungent, irritating odor. Upon condensation, the gas converts to various other forms of formaldehyde (with different chemical formulas) that are of more practical value. One important derivative is the cyclic trimer metaformaldehyde (1,3,5-trioxane) with the formula (CH2O)3. There is also a linear polymer called paraformaldehyde. These compounds have similar chemical properties and are often used interchangeably.
When dissolved in water, formaldehyde also forms a hydrate, methanediol, with the formula H2C(OH)2. This compound also exists in equilibrium with various oligomers (short polymers), depending on the concentration and temperature. A saturated water solution, of about 40% formaldehyde by volume or 37% by mass, is called "100% formalin". A small amount of stabilizer, such as methanol, is usually added to suppress oxidation and polymerization. A typical commercial grade formalin may contain 10–12% methanol in addition to various metallic impurities. The name was long ago genericized from an old trade name "Formalin".
Processes in the upper atmosphere contribute up to 90% of the total formaldehyde in the environment. Formaldehyde is an intermediate in the oxidation (or combustion) of methane, as well as of other carbon compounds, e.g. in forest fires, automobile exhaust, and tobacco smoke. When produced in the atmosphere by the action of sunlight and oxygen on atmospheric methane and other hydrocarbons, it becomes part of smog. Formaldehyde has also been detected in outer space (see below).
Formaldehyde and its adducts are ubiquitous in living organisms. It is formed in the metabolism of endogenous amino acids and is found in the bloodstream of humans and other primates at concentrations of approximately 0.1 millimolar. Experiments in which animals are exposed to an atmosphere containing isotopically labeled formaldehyde have demonstrated that even in deliberately exposed animals, the majority of formaldehyde-DNA adducts found in non-respiratory tissues are derived from endogenously produced formaldehyde.
Formaldehyde does not accumulate in the environment, because it is broken down within a few hours by sunlight or by bacteria present in soil or water. Humans metabolize formaldehyde quickly, converting it to formic acid, so it does not accumulate in the body.
Formaldehyde was the first polyatomic organic molecule detected in the interstellar medium. Since its initial detection in 1969, it has been observed in many regions of the galaxy. Because of the widespread interest in interstellar formaldehyde, it has recently been extensively studied, yielding new extragalactic sources. A proposed mechanism for the formation is the hydrogenation of CO ice, shown below.
Formaldehyde appears to be a useful probe for astrochemists, due to its low reactivity in the gas phase and to the fact that the 110←111 and 211←212 K-doublet transitions are rather clear.
On 11 August 2014, astronomers released studies, using the Atacama Large Millimeter/Submillimeter Array (ALMA) for the first time, that detailed the distribution of HCN, HNC, H2CO, and dust inside the comae of comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON).
Formaldehyde is produced industrially by the catalytic oxidation of methanol. The most common catalysts are silver metal or a mixture of an iron and molybdenum or vanadium oxides. In the commonly used formox process, methanol and oxygen react at ca. 250–400 °C in presence of iron oxide in combination with molybdenum and/or vanadium to produce formaldehyde according to the chemical equation:
The silver-based catalyst usually operates at a higher temperature, about 650 °C. Two chemical reactions on it simultaneously produce formaldehyde: that shown above and the dehydrogenation reaction:
Formaldehyde is a building block in the synthesis of many other compounds of specialised and industrial significance. It exhibits most of the chemical properties of other aldehydes but is more reactive.
Formaldehyde, unlike most aldehydes, oligomerizes spontaneously. The trimer is trioxane and the polymer is called paraformaldehyde. Many cyclic oligomers have been isolated. Similarly, formaldehyde hydrates to give the geminal diol, which condenses further to form oligomers HO(CH2O)nH. Monomeric CH2O is rarely encountered.
Formaldehyde is a good electrophile. With good nucleophiles such as thiols, amines, and even amides, no acid catalyst is required. The resulting hydroxymethyl derivatives typically react further. Thus amines give hexahydro-1,3,5-triazines. Similarly, when combined with hydrogen sulfide, it forms trithiane.
When conducted in the presence of hydrogen chloride, the product is the chloromethyl compound, as described in the Blanc chloromethylation. If the arene is electron-rich, as in phenols, elaborate condensations ensue. With 4-substituted phenols one obtains calixarenes. Phenol results in polymers.
Formaldehyde is a common precursor to more complex compounds and materials. In approximate order of decreasing consumption, products generated from formaldehyde include urea formaldehyde resin, melamine resin, phenol formaldehyde resin, polyoxymethylene plastics, 1,4-butanediol, and methylene diphenyl diisocyanate. The textile industry uses formaldehyde-based resins as finishers to make fabrics crease-resistant. Formaldehyde-based materials are key to the manufacture of automobiles, and used to make components for the transmission, electrical system, engine block, door panels, axles and brake shoes. The value of sales of formaldehyde and derivative products was over $145 billion in 2003, about 1.2% of the gross domestic product (GDP) of the United States and Canada. Including indirect employment, over 4 million people work in the formaldehyde industry across approximately 11,900 plants in the U.S. and Canada.
When treated with phenol, urea, or melamine, formaldehyde produces, respectively, hard thermoset phenol formaldehyde resin, urea formaldehyde resin, and melamine resin. These polymers are common permanent adhesives used in plywood and carpeting. It is used as the wet-strength resin added to sanitary paper products such as (listed in increasing concentrations injected into the paper machine headstock chest) facial tissue, table napkins, and roll towels. They are also foamed to make insulation, or cast into moulded products. Production of formaldehyde resins accounts for more than half of formaldehyde consumption.
Formaldehyde is also a precursor to polyfunctional alcohols such as pentaerythritol, which is used to make paints and explosives. Other formaldehyde derivatives include methylene diphenyl diisocyanate, an important component in polyurethane paints and foams, and hexamine, which is used in phenol-formaldehyde resins as well as the explosive RDX.
An aqueous solution of formaldehyde can be useful as a disinfectant as it kills most bacteria and fungi (including their spores). It is used to produce killed vaccines. Formaldehyde releasers are used as biocides in personal care products such as cosmetics. Although present at levels not normally considered harmful, they are known to cause allergic contact dermatitis in certain sensitised individuals.
Formaldehyde is also approved for use in the manufacture of animal feeds in the US. It is an antimicrobial agent used to maintain complete animal feeds or feed ingredients Salmonella negative for up to 21 days.
Formaldehyde preserves or fixes tissue or cells. The process involves cross-linking of primary amino groups. The European Union has banned the use of formaldehyde due to its carcinogenic properties as a biocide (including embalming) under the Biocidal Products Directive (98/8/EC). Countries with a strong tradition of embalming corpses, such as Ireland and other colder-weather countries, have raised concerns. Despite reports to the contrary, no decision on the inclusion of formaldehyde on Annex I of the Biocidal Products Directive for product-type 22 (embalming and taxidermist fluids) had been made as of September 2009.
Formaldehyde-based crosslinking is exploited in ChIP-on-chip or ChIP-sequencing genomics experiments, where DNA-binding proteins are cross-linked to their cognate binding sites on the chromosome and analyzed to determine what genes are regulated by the proteins. Formaldehyde is also used as a denaturing agent in RNA gel electrophoresis, preventing RNA from forming secondary structures. A solution of 4% formaldehyde fixes pathology tissue specimens at about one mm per hour at room temperature.
In photography, formaldehyde is used in low concentrations for process C-41 (color negative film) stabilizer in the final wash step, as well as in the process E-6 pre-bleach step, to make it unnecessary in the final wash.
The safety of formaldehyde is very complicated. It occurs naturally and is "an essential intermediate in cellular metabolism in mammals and humans." It is not acutely toxic as ingestion of many milliliters is tolerated. The main concerns are associated with chronic (long term) exposure by inhalation. This may happen through three main sources: thermal or chemical decomposition of formaldehyde-based resins, emission from aqueous formaldehyde solutions (i.e. embalming fluids), and the production of formaldehyde resulting from the combustion of a variety of organic compounds (for example, exhaust gases). As formaldehyde resins are used in many construction materials it is one of the more common indoor air pollutants. At concentrations above 0.1 ppm in air formaldehyde can irritate the eyes and mucous membranes, resulting in watery eyes. Formaldehyde inhaled at this concentration may cause headaches, a burning sensation in the throat, and difficulty breathing, and can trigger or aggravate asthma symptoms.
A 1988 Canadian study of houses with urea-formaldehyde foam insulation found that formaldehyde levels as low as 0.046 ppm were positively correlated with eye and nasal irritation. A recent review of studies has shown a strong association between exposure to formaldehyde and the development of childhood asthma. The primary exposure concern is for the workers in the industries producing or using formaldehyde.
The formaldehyde theory of carcinogenesis was proposed in 1978. In 1987 the U.S. EPA classified it as a probable human carcinogen, and after more studies the WHO International Agency for Research on Cancer (IARC) in 1995 also classified it as a probable human carcinogen. Further information and evaluation of all known data led the IARC to reclassify formaldehyde as a known human carcinogen associated with nasal sinus cancer and nasopharyngeal cancer. Recent studies have also shown a positive correlation between exposure to formaldehyde and the development of leukemia, particularly myeloid leukemia. Nasopharyngeal and sinonasal cancers are relatively rare, with a combined annual incidence in the United States of < 4,000 cases. About 25,000 cases of myeloid leukemia occur in the United States each year. Workplace exposure to inhaled chemicals is among the most important risk factors for sinonasal cancers. Professionals exposed to formaldehyde in their occupation, such as funeral industry workers and embalmers, showed an increased risk of leukemia and brain cancer compared with the general population. Other factors are important in determining individual risk for the development of leukemia or nasopharyngeal cancer.
In the residential environment, formaldehyde exposure comes from a number of different routes; formaldehyde can off-gas from wood products, such as plywood or particle board, but it is produced by paints, varnishes, floor finishes, and cigarette smoking as well. In July 2016, the EPA released a prepublication version of its final rule on Formaldehyde Emission Standards for Composite Wood Products. These new rules impact manufacturers, importers, distributors, and retailers of products containing composite wood, including fiberboard, particleboard, and various laminated products, who must comply with more stringent record-keeping and labeling requirements.
The United States Environmental Protection Agency (EPA) allows no more than 0.016 ppm formaldehyde in the air in new buildings constructed for that agency. A U.S. Environmental Protection Agency study found a new home measured 0.076 ppm when brand new and 0.045 ppm after 30 days. The Federal Emergency Management Agency (FEMA) has also announced limits on the formaldehyde levels in trailers purchased by that agency. The EPA recommends the use of "exterior-grade" pressed-wood products with phenol instead of urea resin to limit formaldehyde exposure, since pressed-wood products containing formaldehyde resins are often a significant source of formaldehyde in homes.
For most people, irritation from formaldehyde is temporary and reversible, though formaldehyde can cause allergies and is part of the standard patch test series. In 2005–06, it was the seventh-most-prevalent allergen in patch tests (9.0%). People with formaldehyde allergy are advised to avoid formaldehyde releasers as well (e.g., Quaternium-15, imidazolidinyl urea, and diazolidinyl urea). People who suffer allergic reactions to formaldehyde tend to display lesions on the skin in the areas that have had direct contact with the substance, such as the neck or thighs (often due to formaldehyde released from permanent press finished clothing) or dermatitis on the face (typically from cosmetics). Formaldehyde has been banned in cosmetics in both Sweden and Japan. The eyes are most sensitive to formaldehyde exposure: The lowest level at which many people can begin to smell formaldehyde is about 0.05 ppm and the highest level is 1 ppm. The maximum concentration value at the workplace is 0.3 ppm. In controlled chamber studies, individuals begin to sense eye irritation at about 0.5 ppm; 5 to 20 percent report eye irritation at 0.5 to 1 ppm; and greater certainty for sensory irritation occurred at 1 ppm and above. While some agencies have used a level as low as 0.1 ppm as a threshold for irritation, the expert panel found that a level of 0.3 ppm would protect against nearly all irritation. In fact, the expert panel found that a level of 1.0 ppm would avoid eye irritation—the most sensitive endpoint—in 75–95% of all people exposed.
Formaldehyde levels in building environments are affected by a number of factors. These include the potency of formaldehyde-emitting products present, the ratio of the surface area of emitting materials to volume of space, environmental factors, product age, interactions with other materials, and ventilation condition. Formaldehyde emits from a variety of construction materials, furnishings, and consumer products. The three products that emit the highest concentrations are medium density fiberboard, hardwood plywood, and particle board. Environmental factors such as temperature and relative humidity can elevate levels because formaldehyde has a high vapor pressure. Formaldehyde levels from building materials are the highest when a building first opens because materials would have less time to off-gas. Formaldehyde levels decrease over time as the sources suppress.
Formaldehyde levels in air can be sampled and tested in several ways, including impinger, treated sorbent, and passive monitors. The National Institute for Occupational Safety and Health (NIOSH) has measurement methods numbered 2016, 2541, 3500, and 3800.
Studies on the interactions between formaldehyde and proteins at the molecular level have been reported on the effects of the body's carrier protein, serum albumin. The binding of formaldehyde loosens the skeletal structure of albumin and exposure of aromatic ring amino acids in the internal hydrophobic region. Symptoms may affect personal awareness, making one feel tired or fatigued.
Formaldehyde inhalation has also shown to cause oxidative stress and inflammation in animals. Mice studied over an exposure to a high dose of formaldehyde (3ppm), showed increased NO−
3 levels in plasma. This result suggests that FA inhalation either decreased NO production or increased NO scavenging, which may be an anti-stress mechanism in the body. Formaldehyde inhalation changes the sensitivity of immune system, which influences oxidative stress.
In June 2011, the twelfth edition of the National Toxicology Program (NTP) Report on Carcinogens (RoC) changed the listing status of formaldehyde from "reasonably anticipated to be a human carcinogen" to "known to be a human carcinogen." Concurrently, a National Academy of Sciences (NAS) committee was convened and issued an independent review of the draft United States Environmental Protection Agency IRIS assessment of formaldehyde, providing a comprehensive health effects assessment and quantitative estimates of human risks of adverse effects.
Several web articles claim that formaldehyde has been banned from manufacture or import into the European Union (EU) under REACH (Registration, Evaluation, Authorization, and restriction of Chemical substances) legislation. This is misinformation, as official EU chemical databases contradict these claims as of February 19, 2010. This misconception has gained some ground. Formaldehyde is not listed in the Annex I of Regulation (EC) No 689/2008 (export and import of dangerous chemicals regulation), nor on a priority list for risk assessment. However, formaldehyde is banned from use in certain applications (preservatives for liquid-cooling and processing systems, slimicides, metalworking-fluid preservatives, and antifouling products) under the Biocidal Products Directive. In the EU, the maximum allowed concentration of formaldehyde in finished products is 0.2%, and any product that exceeds 0.05% has to include a warning that the product contains formaldehyde.
In the United States, Congress passed a bill July 7, 2010 regarding the use of formaldehyde in hardwood plywood, particle board, and medium density fiberboard. The bill limited the allowable amount of formaldehyde emissions from these wood products to .09 ppm, and required companies to meet this standard by January 2013. Formaldehyde was declared a toxic substance by the 1999 Canadian Environmental Protection Act.
|"Episode 202: Where Have All the FEMA Trailers Gone? Tracing Toxicity from Bust to Boom", Distillations, September 2, 2015, Science History Institute|
|Where Have All the Trailers Gone?, Video by Mariel Carr (Videographer) & Nick Shapiro (Researcher), 2015, Science History Institute|
In the U.S. the Federal Emergency Management Agency (FEMA) provided travel trailers, recreational park trailers and manufactured homes starting in 2006 for habitation by residents of the U.S. gulf coast displaced by Hurricane Katrina and Hurricane Rita. Some of the people who moved into the FEMA trailers complained of breathing difficulties, nosebleeds, and persistent headaches. Formaldehyde-catalyzed resins were used in the production of these homes.
The United States Centers For Disease Control and Prevention (CDC) performed indoor air quality testing for formaldehyde in some of the units. On February 14, 2008, the CDC announced that potentially hazardous levels of formaldehyde were found in many of the travel trailers and manufactured homes provided by the agency. The CDC's preliminary evaluation of a scientifically established random sample of 519 travel trailers and manufactured homes tested between December 21, 2007, and January 23, 2008 (2+ years after manufacture), showed average levels of formaldehyde in all units of about 0.077 parts per million (ppm). Long-term exposure to levels in this range can be linked to an increased risk of cancer and, at levels above this range, there can also be a risk of respiratory illness. These levels are higher than expected in indoor air, where levels are commonly in the range of 0.01–0.02 ppm, and are higher than the Agency for Toxic Substance Disease Registry (ATSDR, division of the CDC) Minimal Risk Level (MRL) of 0.008 ppm. Levels measured ranged from 0.003 ppm to 0.59 ppm.
FEMA, which requested the testing by the CDC, said it would work aggressively to relocate all residents of the temporary housing as soon as possible. Lawsuits were filed against FEMA trailer manufacturers as a result of the exposures. As of 2012, U.S. District Judge Kurt D. Engelhardt of New Orleans approved a $42.6 million class-action lawsuit settlement for the plaintiffs, who included roughly 55,000 residents of Louisiana, Mississippi, Alabama and Texas. The defendants included two dozen manufacturers who built mobile homes for the Federal Emergency Management Agency (FEMA), including Gulf Stream Coach Inc., Forest River Inc., Vanguard LLC and Monaco Coach Corp. A separate $5.1 million settlement dealt with claims against FEMA contractors including Shaw Environmental Inc., Bechtel Corp., Fluor Enterprises Inc. and CH2M Hill Constructors Inc., who were responsible for installing and maintaining the units.
Also in the U.S., problems arose in trailers again provided by FEMA to residents displaced by the Iowa floods of 2008. Several months after moving to the trailers, occupants reported violent coughing, headaches, as well as asthma, bronchitis, and other problems. Tests showed that in some trailers, levels of formaldehyde exceeded the limits recommended by the U.S. Environmental Protection Agency and American Lung Association. The associated publicity has resulted in additional testing to begin in November.
Formaldehyde occurs naturally and is "an essential intermediate in cellular metabolism in mammals and humans." At high concentrations it is probably unhealthy. Scandals have broken in both the 2005 Indonesia food scare and 2007 Vietnam food scare regarding the addition of formaldehyde to foods to extend shelf life. In 2011, after a four-year absence, Indonesian authorities found foods with formaldehyde being sold in markets in a number of regions across the country. In August 2011, at least at two Carrefour supermarkets, the Central Jakarta Livestock and Fishery Sub-Department found a sweet glutinous rice drink (cendol) contained 10 parts per million of formaldehyde. In 2014, the owner of two noodle factories in Bogor, Indonesia; was arrested for using formaldehyde in noodles. 50 kg of formaldehyde was confiscated. Foods known to be contaminated included noodles, salted fish, and tofu. Chicken and beer were also rumored to be contaminated. In some places, such as China, manufacturers still use formaldehyde illegally as a preservative in foods, which exposes people to formaldehyde ingestion. In humans, the ingestion of formaldehyde has been shown to cause vomiting, abdominal pain, dizziness, and in extreme cases can cause death. Testing for formaldehyde is by blood and/or urine by gas chromatography-mass spectrometry. Other methods include infrared detection, gas detector tubes, etc., of which HPLC is the most sensitive. In the early 1900s, it was frequently added by US milk plants to milk bottles as a method of pasteurization due to the lack of knowledge regarding formaldehyde's toxicity.
In 2011 in Nakhon Ratchasima, Thailand, truckloads of rotten chicken were exposed to formaldehyde in which "a large network," including 11 slaughterhouses run by a criminal gang, were implicated. In 2012, 1 billion rupiah (almost US$100,000) of fish imported from Pakistan to Batam, Indonesia, were found laced with formaldehyde.
Formalin contamination of foods has been reported in Bangladesh, with stores and supermarkets selling fruits, fishes, and vegetables that have been treated with formalin to keep them fresh. However, in 2015, a Formalin Control Bill was passed in the Parliament of Bangladesh with a provision of life-term imprisonment as the maximum punishment and in addition 2,000,000 BDT as fine but not less than 500,000 BDT for importing, production or hoarding of formalin without license.
Formaldehyde is used to inactivate bacterial products for toxoid vaccines, (these are vaccines that use an inactive bacterial toxin to produce immunity.) It is also used to kill unwanted viruses and bacteria that might contaminate the vaccine during production. Most formaldehyde is removed from the vaccine before it is packaged.
An aldehyde is an organic compound containing a functional group with the structure −CHO, consisting of a carbonyl center (a carbon double-bonded to oxygen) with the carbon atom also bonded to hydrogen and to an R group, which is any generic alkyl or side chain. The group—without R—is the aldehyde group, also known as the formyl group. Aldehydes are common in organic chemistry, and many fragrances are aldehydes.Bakelite
Bakelite ( BAY-kəl-eyet; sometimes spelled Baekelite) or polyoxybenzylmethylenglycolanhydride was the first plastic made from synthetic components. It is a thermosetting phenol formaldehyde resin, formed from a condensation reaction of phenol with formaldehyde. It was developed by the Belgian-American chemist Leo Baekeland in Yonkers, New York, in 1907.
Bakelite was patented on December 7, 1909. The creation of a synthetic plastic was revolutionary for its electrical nonconductivity and heat-resistant properties in electrical insulators, radio and telephone casings and such diverse products as kitchenware, jewelry, pipe stems, children's toys, and firearms. The "retro" appeal of old Bakelite products has made them collectible.Bakelite was designated a National Historic Chemical Landmark on November 9, 1993, by the American Chemical Society in recognition of its significance as the world's first synthetic plastic.Contact dermatitis
Contact dermatitis is a type of inflammation of the skin.
It results from either exposure to allergens (allergic contact dermatitis) or irritants (irritant contact dermatitis). Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight. Diagnosis of allergic contact dermatitis can often be supported by patch testing.Cosmetology
Cosmetology (from Greek κοσμητικός, kosmētikos, "beautifying"; and -λογία, -logia) is the study and application of beauty treatment. Branches of specialty include hairstyling, skin care, cosmetics, manicures/pedicures, non permanent hair removal such as waxing and sugaring and permanent hair removal processes such as electrology and intense pulsed light (IPL).Engineered wood
Engineered wood, also called composite wood, man-made wood, or manufactured board, includes a range of derivative wood products which are manufactured by binding or fixing the strands, particles, fibres, or veneers or boards of wood, together with adhesives, or other methods of fixation to form composite materials. These products are engineered to precise design specifications which are tested to meet national or international standards. Engineered wood products are used in a variety of applications, from home construction to commercial buildings to industrial products. The products can be used for joists and beams that replace steel in many building projects.Typically, engineered wood products are made from the same hardwoods and softwoods used to manufacture lumber. Sawmill scraps and other wood waste can be used for engineered wood composed of wood particles or fibers, but whole logs are usually used for veneers, such as plywood, MDF or particle board. Some engineered wood products, like oriented strand board (OSB), can use trees from the poplar family, a common but non-structural species.
Alternatively, it is also possible to manufacture similar engineered bamboo from bamboo; and similar engineered cellulosic products from other lignin-containing materials such as rye straw, wheat straw, rice straw, hemp stalks, kenaf stalks, or sugar cane residue, in which case they contain no actual wood but rather vegetable fibers.
Flat pack furniture is typically made out of man-made wood due to its low manufacturing costs and its low weight.Glycolonitrile
Glycolonitrile, also called hydroxyacetonitrile or formaldehyde cyanohydrin, is the organic compound with the formula HOCH2CN. It is the simplest cyanohydrin and it is derived from formaldehyde. It is a colourless liquid that dissolves in water and ether. Because glycolonitrile decomposes readily into formaldehyde and hydrogen cyanide, it is listed as an extremely hazardous substance. In January 2019, astronomers reported the detection of glycolonitrile, another possible building block of life among other such molecules, in outer space.Interstellar formaldehyde
Interstellar formaldehyde (a topic relevant to astrochemistry) was first discovered in 1969 by L. Snyder et al. using the National Radio Astronomy Observatory. Formaldehyde (H2CO) was detected by means of the 111 - 110 ground state rotational transition at 4830 MHz. On 11 August 2014, astronomers released studies, using the Atacama Large Millimeter/Submillimeter Array (ALMA) for the first time, that detailed the distribution of HCN, HNC, H2CO, and dust inside the comae of comets C/2012 F6 (Lemmon) and C/2012 S1 (ISON).List of vaccine ingredients
This list of vaccine ingredients indicates the culture media used in the production of common vaccines and the excipients they contain, as published by the United States Centers for Disease Control and Prevention and Food and Drug Administration. Vaccine ingredients and production in other nations are substantially the same. Also listed are substances used in the manufacturing process.To read the prescribing information for each individual vaccine, see List of Licensed VaccinesMedium-density fibreboard
Medium-density fibreboard (MDF) is an engineered wood product made by breaking down hardwood or softwood residuals into wood fibres, often in a defibrator, combining it with wax and a resin binder, and forming panels by applying high temperature and pressure. MDF is generally denser than plywood. It is made up of separated fibres, but can be used as a building material similar in application to plywood. It is stronger and much denser than particle board.The name derives from the distinction in densities of fibreboard. Large-scale production of MDF began in the 1980s, in both North America and Europe.Melamine resin
Melamine resin or melamine formaldehyde (also shortened to melamine) is a resin with melamine rings terminated with multiple hydroxyl groups derived from formaldehyde. This thermosetting plastic material is made from melamine and formaldehyde. In its butylated form, it is dissolved in n-butanol and xylene. It is then used to cross-link with alkyd, epoxy, acrylic, and polyester resins, used in surface coatings. There are many types, varying from very slow to very fast curing.
It was discovered by William F. Talbot, who applied to patent it on December 12, 1936.Methanol
Methanol, also known as methyl alcohol among others, is a chemical with the formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated MeOH). Methanol acquired the name wood alcohol because it was once produced chiefly by the destructive distillation of wood. Today, methanol is mainly produced industrially by hydrogenation of carbon monoxide.Methanol is the simplest alcohol, consisting of a methyl group linked to a hydroxyl group. It is a light, volatile, colorless, flammable liquid with a distinctive odor similar to that of ethanol (drinking alcohol). Methanol is however far more toxic than ethanol. At room temperature, it is a polar liquid. With more than 20 million tons produced annually, it is used as a precursor to other commodity chemicals, including formaldehyde, acetic acid, methyl tert-butyl ether, as well as a host of more specialized chemicals.Methylococcaceae
The Methylococcaceae are a family of bacteria that obtain their carbon and energy from methane, called methanotrophs.They comprise the type I methanotrophs, in contrast to the Methylocystaceae or type II methanotrophs. They belong among the gamma subdivision of the Proteobacteria, and are typically given their own order.
The Methylococcaceae have internal membranes in the form of flattened discs, perpendicular to the cell wall. Methane is oxidized to give formaldehyde, which is fixed by a process called the RuMP cycle (Ribulose Monophosphate Cycle). Here formaldehyde is combined with sugar ribulose, producing hexulose. This, in turn, is broken down to produce glyceraldehyde, which is used to produce new ribulose and other organic compounds. Catabolism does not involve a complete citric acid cycle.Some species of the Methylococcaceae have formed with certain marine mussels endosymbiotic relationships.Oriented strand board
Oriented strand board (OSB), also known as flakeboard, sterling board and aspenite in British English, is a type of engineered wood similar to particle board, formed by adding adhesives and then compressing layers of wood strands (flakes) in specific orientations. It was invented by Armin Elmendorf in California in 1963. OSB may have a rough and variegated surface with the individual strips of around 2.5 cm × 15 cm (1.0 by 5.9 inches), lying unevenly across each other and comes in a variety of types and thicknesses.Paraformaldehyde
Paraformaldehyde (PFA) is the smallest polyoxymethylene, the polymerization product of formaldehyde with a typical degree of polymerization of 8–100 units. Paraformaldehyde commonly has a slight odor of formaldehyde due to decomposition. Paraformaldehyde is a poly-acetal.Particle board
Particle board – also known as particleboard, low-density fibreboard (LDF), and chipboard – is an engineered wood product manufactured from wood chips, sawmill shavings, or even sawdust, and a synthetic resin or other suitable binder, which is pressed and extruded. Oriented strand board, also known as flakeboard, waferboard, or chipboard, is similar but uses machined wood flakes offering more strength. All of these are composite materials that belong to the spectrum of fiberboard products.Phenol formaldehyde resin
Phenol formaldehyde resins (PF) or phenolic resins are synthetic polymers obtained by the reaction of phenol or substituted phenol with formaldehyde. Used as the basis for Bakelite, PFs were the first commercial synthetic resins (plastics). They have been widely used for the production of molded products including billiard balls, laboratory countertops, and as coatings and adhesives. They were at one time the primary material used for the production of circuit boards but have been largely replaced with epoxy resins and fiberglass cloth, as with fire-resistant FR-4 circuit board materials.
There are two main production methods. One reacts phenol and formaldehyde directly to produce a thermosetting network polymer, while the other restricts the formaldehyde to produce a prepolymer known as novolac which can be moulded and then cured with the addition of more formaldehyde and heat. There are many variations in both production and input materials that are used to produce a wide variety of resins for special purposes.The Physical Impossibility of Death in the Mind of Someone Living
The Physical Impossibility of Death in the Mind of Someone Living is an artwork created in 1991 by Damien Hirst, an English artist and a leading member of the "Young British Artists" (or YBA). It consists of a tiger shark preserved in formaldehyde in a vitrine. It was originally commissioned in 1991 by Charles Saatchi, who sold it in 2004, to Steven A. Cohen for an undisclosed amount, widely reported to have been at least $8 million. However, the title of Don Thompson's book, The $12 Million Stuffed Shark: The Curious Economics of Contemporary Art, suggests a higher figure.
Owing to deterioration of the original 14-foot (4.3 m) tiger shark, it was replaced with a new specimen in 2006. It was on loan to the Metropolitan Museum of Art in New York City from 2007 to 2010.It is considered the iconic work of British art in the 1990s, and has become a symbol of Britart worldwide.Urea-formaldehyde
Urea-formaldehyde, also known as urea-methanal, so named for its common synthesis pathway and overall structure, is a non-transparent thermosetting resin or polymer. It is produced from urea and formaldehyde. These resins are used in adhesives, finishes, particle board, medium-density fibreboard (MDF), and molded objects. UF and related amino resins are a class of thermosetting resins of which urea-formaldehyde resins make up 80% produced globally. Examples of amino resins use include in automobile tires to improve the bonding of rubber to tire cord, in paper for improving tear strength, in molding electrical devices, jar caps, etc.Wood glue
Wood glue is an adhesive used to tightly bond pieces of wood together. Many substances have been used as glues.