E (named e /iː/, plural ees) is the fifth letter and the second vowel in the modern English alphabet and the ISO basic Latin alphabet. It is the most commonly used letter in many languages, including Czech, Danish, Dutch, English, French, German, Hungarian, Latin, Latvian, Norwegian, Spanish, and Swedish.
|Writing system||Latin script|
|Language of origin||Latin language|
|Time period||c. 700 BC to present|
|Descendants|| • ♯|
|Other letters commonly used with||ee|
The Latin letter 'E' differs little from its source, the Greek letter epsilon, 'Ε'. This in turn comes from the Semitic letter hê, which has been suggested to have started as a praying or calling human figure (hillul 'jubilation'), and was probably based on a similar Egyptian hieroglyph that indicated a different pronunciation. In Semitic, the letter represented /h/ (and /e/ in foreign words); in Greek, hê became the letter epsilon, used to represent /e/. The various forms of the Old Italic script and the Latin alphabet followed this usage.
Although Middle English spelling used ⟨e⟩ to represent long and short /e/, the Great Vowel Shift changed long /eː/ (as in 'me' or 'bee') to /iː/ while short /ɛ/ (as in 'met' or 'bed') remained a mid vowel. In other cases, the letter is silent, generally at the end of words.
In the orthography of many languages it represents either [e], [e̞], [ɛ], or some variation (such as a nasalized version) of these sounds, often with diacritics (as: ⟨e ê é è ë ē ĕ ě ẽ ė ẹ ę ẻ⟩) to indicate contrasts. Less commonly, as in French, German, or Saanich, ⟨e⟩ represents a mid-central vowel /ə/. Digraphs with ⟨e⟩ are common to indicate either diphthongs or monophthongs, such as ⟨ea⟩ or ⟨ee⟩ for /iː/ or /eɪ/ in English, ⟨ei⟩ for /aɪ/ in German, and ⟨eu⟩ for /ø/ in French or /ɔɪ/ in German.
'E' is the most common (or highest-frequency) letter in the English alphabet (starting off the typographer's phrase ETAOIN SHRDLU) and several other European languages, which has implications in both cryptography and data compression. In the story "The Gold-Bug" by Edgar Allan Poe, a character figures out a random character code by remembering that the most used letter in English is E. This makes it a hard and popular letter to use when writing lipograms. Ernest Vincent Wright's Gadsby (1939) is considered a "dreadful" novel, and supposedly "at least part of Wright's narrative issues were caused by language limitations imposed by the lack of E." Both Georges Perec's novel A Void (La Disparition) (1969) and its English translation by Gilbert Adair omit 'e' and are considered better works.
|Unicode name||LATIN CAPITAL LETTER E||LATIN SMALL LETTER E|
|Numeric character reference||E||E||e||e|
|NATO phonetic||Morse code|
|Signal flag||Flag semaphore||American manual alphabet (ASL fingerspelling)||Braille |
In British Sign Language (BSL), the letter 'e' is signed by extending the index finger of the right hand touching the tip of index on the left hand, with all fingers of left hand open.
E. I. du Pont de Nemours and Company, commonly referred to as DuPont (), is an American conglomerate that was founded in July 1802 in Wilmington, Delaware, as a gunpowder mill by French-American chemist and industrialist Éleuthère Irénée du Pont.
In the 20th century, DuPont developed many polymers such as Vespel, neoprene, nylon, Corian, Teflon, Mylar, Kapton, Kevlar, Zemdrain, M5 fiber, Nomex, Tyvek, Sorona, Corfam, and Lycra. DuPont developed Freon (chlorofluorocarbons) for the refrigerant industry, and later other refrigerants. It also developed synthetic pigments and paints including ChromaFlair.
In 2014, DuPont was the world's fourth-largest chemical company based on market capitalization and eighth-largest based on revenue. On August 31, 2017, it merged with the Dow Chemical Company to create DowDuPont, the world's largest chemical company in terms of sales, of which DuPont is now a subsidiary. Its stock price is a component of the Dow Jones Industrial Average.E-book
An electronic book, also known as an e-book or eBook, is a book publication made available in digital form, consisting of text, images, or both, readable on the flat-panel display of computers or other electronic devices. Although sometimes defined as "an electronic version of a printed book", some e-books exist without a printed equivalent. E-books can be read on dedicated e-reader devices, but also on any computer device that features a controllable viewing screen, including desktop computers, laptops, tablets and smartphones.
In the 2000s, there was a trend of print and e-book sales moving to the Internet, where readers buy traditional paper books and e-books on websites using e-commerce systems. With print books, readers are increasingly browsing through images of the covers of books on publisher or bookstore websites and selecting and ordering titles online; the paper books are then delivered to the reader by mail or another delivery service. With e-books, users can browse through titles online, and then when they select and order titles, the e-book can be sent to them online or the user can download the e-book. At the start of 2012 in the U.S., more e-books were published online than were distributed in hardcover.The main reasons for people buying e-books online are possibly lower prices, increased comfort (as they can buy from home or on the go with mobile devices) and a larger selection of titles. With e-books, "[e]lectronic bookmarks make referencing easier, and e-book readers may allow the user to annotate pages." "Although fiction and non-fiction books come in e-book formats, technical material is especially suited for e-book delivery because it can be [electronically] searched" for keywords. In addition, for programming books, code examples can be copied. The amount of e-book reading is increasing in the U.S.; by 2014, 28% of adults had read an e-book, compared to 23% in 2013. This is increasing, because by 2014 50% of American adults had an e-reader or a tablet, compared to 30% owning such devices in 2013.E-commerce
E-commerce is the activity of buying or selling of products on online services or over the Internet. Electronic commerce draws on technologies such as mobile commerce, electronic funds transfer, supply chain management, Internet marketing, online transaction processing, electronic data interchange (EDI), inventory management systems, and automated data collection systems.
Modern electronic commerce typically uses the World Wide Web for at least one part of the transaction's life cycle although it may also use other technologies such as e-mail. Typical e-commerce transactions include the purchase of online books (such as Amazon) and music purchases (music download in the form of digital distribution such as iTunes Store), and to a less extent, customized/personalized online liquor store inventory services. There are three areas of e-commerce: online retailing, electric markets, and online auctions. E-commerce is supported by electronic business.E-commerce businesses may also employ some or all of the followings:
Online shopping for retail sales direct to consumers via Web sites and mobile apps, and conversational commerce via live chat, chatbots, and voice assistants
Providing or participating in online marketplaces, which process third-party business-to-consumer or consumer-to-consumer sales
Business-to-business buying and selling;
Gathering and using demographic data through web contacts and social media
Business-to-business (B2B) electronic data interchange
Marketing to prospective and established customers by e-mail or fax (for example, with newsletters)
Engaging in pretail for launching new products and services
Online financial exchanges for currency exchanges or trading purposes.E.T. the Extra-Terrestrial
E.T. the Extra-Terrestrial is a 1982 American science fiction film produced and directed by Steven Spielberg, and written by Melissa Mathison. It features special effects by Carlo Rambaldi and Dennis Muren, and stars Henry Thomas, Dee Wallace, Peter Coyote, Robert MacNaughton, Drew Barrymore, and Pat Welsh. It tells the story of Elliott (Thomas), a boy who befriends an extraterrestrial, dubbed "E.T.", who is stranded on Earth. Elliott and his siblings help E.T. return to his home planet, while attempting to keep him hidden from the government.
The concept was based on an imaginary friend Spielberg created after his parents' divorce in 1960. In 1980, Spielberg met Mathison and developed a new story from the stalled sci-fi horror film project Night Skies. It was filmed from September to December 1981 in California on a budget of $10.5 million USD. Unlike most films, it was shot in rough chronological order, to facilitate convincing emotional performances from the young cast.
Released on June 11, 1982, by Universal Pictures, E.T. was an immediate blockbuster, surpassing Star Wars to become the highest-grossing film of all time—a record it held for eleven years until Jurassic Park, another Spielberg-directed film, surpassed it in 1993.
Considered one of the finest movies of its generation, it was widely acclaimed by critics as a timeless story of friendship, and it ranks as the greatest science fiction film ever made in a Rotten Tomatoes survey. In 1994, it was selected for preservation in the United States National Film Registry as being "culturally, historically, or aesthetically significant". It was re-released in 1985, and then again in 2002, to celebrate its 20th anniversary, with altered shots and additional scenes.E (mathematical constant)
The number e is a mathematical constant that is the base of the natural logarithm: the unique number whose natural logarithm is equal to one. It is approximately equal to 2.71828, and is the limit of (1 + 1/n)n as n approaches infinity, an expression that arises in the study of compound interest. It can also be calculated as the sum of the infinite series
The constant can be characterized in many different ways. For example, e can be defined as the unique positive number a such that the graph of the function y = ax has unit slope at x = 0. The function f(x) = ex is called the (natural) exponential function, and is the unique exponential function equal to its own derivative. The natural logarithm, or logarithm to base e, is the inverse function to the natural exponential function. The natural logarithm of a number k > 1 can be defined directly as the area under the curve y = 1/x between x = 1 and x = k, in which case e is the value of k for which this area equals one (see image). There are alternative characterizations.
Sometimes called Euler's number after the Swiss mathematician Leonhard Euler, e is not to be confused with γ, the Euler–Mascheroni constant, sometimes called simply Euler's constant. The number e is also known as Napier's constant, but Euler's choice of the symbol e is said to have been retained in his honor. The constant was discovered by the Swiss mathematician Jacob Bernoulli while studying compound interest.
The number e is of eminent importance in mathematics, alongside 0, 1, π and i. All five of these numbers play important and recurring roles across mathematics, and are the five constants appearing in one formulation of Euler's identity. Like the constant π, e is irrational: it is not a ratio of integers. Also like π, e is transcendental: it is not a root of any non-zero polynomial with rational coefficients. The numerical value of e truncated to 50 decimal places isEazy-E
Eric Lynn Wright (September 7, 1964 – March 26, 1995), known professionally as Eazy-E, was an American rapper, record producer, and entrepreneur. Dubbed the "Godfather of Gangsta Rap", he gained prominence for his work with N.W.A, where he has been credited for pushing the boundaries of lyrical and visual content in mainstream popular music.
Born and raised in Compton, California, Eazy-E faced several legal troubles before founding the Ruthless Records record label in 1986. After beginning a short solo career, where he worked heavily with Ice Cube and Dr. Dre, the trio came together to form the group N.W.A later that year. As a member of the group, he released the controversial album, Straight Outta Compton (1988), which tackled many socio-political issues. The album has been regarded as one of the greatest albums of all-time, and one of the most influential in the genre. The group released their final studio album three years later, and disbanded shortly after, due to long-standing financial disputes.
Eazy-E then resumed his solo career, where he released two EPs, which drew inspiration from funk music, contemporary hip-hop, and comedians. He also engaged in a high-profile feud with Dr. Dre, before being hospitalized with AIDS in 1995. He died a month after his hospitalization.Electric field
An electric field surrounds an electric charge, and exerts force on other charges in the field, attracting or repelling them. Electric field is sometimes abbreviated as E-field. The electric field is defined mathematically as a vector field that associates to each point in space the (electrostatic or Coulomb) force per unit of charge exerted on an infinitesimal positive test charge at rest at that point. The SI unit for electric field strength is volt per meter (V/m). Newtons per coulomb (N/C) is also used as a unit of electric field strength. Electric fields are created by electric charges, or by time-varying magnetic fields. Electric fields are important in many areas of physics, and are exploited practically in electrical technology. On an atomic scale, the electric field is responsible for the attractive force between the atomic nucleus and electrons that holds atoms together, and the forces between atoms that cause chemical bonding. Electric fields and magnetic fields are both manifestations of the electromagnetic force, one of the four fundamental forces (or interactions) of nature.Electronic cigarette
An electronic cigarette or e-cigarette is a handheld electronic device that simulates the experience of smoking a cigarette. It works by heating a liquid which generates an aerosol, or "vapor", that is inhaled by the user. Using e-cigarettes is commonly referred to as vaping. The liquid in the e-cigarette, called e-liquid, or e-juice, is usually made of nicotine, propylene glycol, glycerine, and flavorings. Not all e-liquids contain nicotine.The health risks of e-cigarettes are uncertain. They are likely safer than tobacco cigarettes, but are of unclear effect in relation to other methods of stopping smoking. Their long-term health effects are not known. They may help some smokers quit. When used by non-smokers, e-cigarettes can lead to nicotine addiction, and there is concern that children could start smoking after using e-cigarettes. So far, no serious adverse effects have been reported in trials. Less serious adverse effects include throat and mouth irritation, vomiting, nausea, and coughing.The majority of toxic chemicals found in tobacco smoke are absent in e-cigarette aerosol. Those present are mostly below 1% of the corresponding levels in tobacco smoke. The aerosol can contain toxicants and traces of heavy metals at levels permissible in inhalation medicines, and potentially harmful chemicals not found in tobacco smoke at concentrations permissible by workplace safety standards. However, chemical concentrations may exceed the stricter public safety limits.The modern e-cigarette was invented in 2003 by Chinese pharmacist Hon Lik. As of 2018 most e-cigarettes are made in China. Their global use has risen exponentially since they were first sold in 2004; their use is widespread in the United States and the United Kingdom. Reasons for using e-cigarettes include trying to quit smoking, reduce risk, or save money, though some use them recreationally. As of 2014, the majority of users still smoke tobacco. There are concerns that dual use of tobacco products and e-cigarettes may "delay or deter quitting". About 60% of UK users are smokers and roughly 40% are ex-smokers. In the UK use among never-smokers was negligible. Because of overlap with tobacco laws and medical drug policies, e-cigarette legislation is debated in many countries. A European directive of 2016 set standards for liquids, vaporizers, ingredients and child-proof liquid containers. As of August 2016, the US FDA extended its regulatory power to include e-cigarettes. There are around 500 brands of e-cigarettes, with global sales in excess of US$7 billion.Embraer E-Jet family
The Embraer E-Jet family is a series of narrow-body short- to medium-range twin-engine jet airliners, carrying 66 to 124 passengers commercially, manufactured by Brazilian aerospace manufacturer Embraer. The aircraft family was first introduced at the Paris Air Show in 1999 and entered production in 2002. The series has been a commercial success primarily due to its ability to efficiently serve lower-demand routes while offering many of the same amenities and features of larger jets. The aircraft is used by mainline and regional airlines around the world but has proven particularly popular with regional airlines in the United States.Escherichia coli
Escherichia coli (), also known as E. coli (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in their hosts, and are occasionally responsible for product recalls due to food contamination. The harmless strains are part of the normal microbiota of the gut, and can benefit their hosts by producing vitamin K2, and preventing colonization of the intestine with pathogenic bacteria, having a symbiotic relationship. E. coli is expelled into the environment within fecal matter. The bacterium grows massively in fresh fecal matter under aerobic conditions for 3 days, but its numbers decline slowly afterwards.E. coli and other facultative anaerobes constitute about 0.1% of gut microbiota, and fecal–oral transmission is the major route through which pathogenic strains of the bacterium cause disease. Cells are able to survive outside the body for a limited amount of time, which makes them potential indicator organisms to test environmental samples for fecal contamination. A growing body of research, though, has examined environmentally persistent E. coli which can survive for extended periods outside a host.The bacterium can be grown and cultured easily and inexpensively in a laboratory setting, and has been intensively investigated for over 60 years. E. coli is a chemoheterotroph whose chemically defined medium must include a source of carbon and energy. E. coli is the most widely studied prokaryotic model organism, and an important species in the fields of biotechnology and microbiology, where it has served as the host organism for the majority of work with recombinant DNA. Under favorable conditions, it takes up to 20 minutes to reproduce.Expected value
In probability theory, the expected value of a random variable, intuitively, is the long-run average value of repetitions of the same experiment it represents. For example, the expected value in rolling a six-sided die is 3.5, because the average of all the numbers that come up is 3.5 as the number of rolls approaches infinity (see § Examples for details). In other words, the law of large numbers states that the arithmetic mean of the values almost surely converges to the expected value as the number of repetitions approaches infinity. The expected value is also known as the expectation, mathematical expectation, EV, average, mean value, mean, or first moment.
More practically, the expected value of a discrete random variable is the probability-weighted average of all possible values. In other words, each possible value the random variable can assume is multiplied by its probability of occurring, and the resulting products are summed to produce the expected value. The same principle applies to an absolutely continuous random variable, except that an integral of the variable with respect to its probability density replaces the sum. The formal definition subsumes both of these and also works for distributions which are neither discrete nor absolutely continuous; the expected value of a random variable is the integral of the random variable with respect to its probability measure.The expected value does not exist for random variables having some distributions with large "tails", such as the Cauchy distribution. For random variables such as these, the long-tails of the distribution prevent the sum or integral from converging.
The expected value is a key aspect of how one characterizes a probability distribution; it is one type of location parameter. By contrast, the variance is a measure of dispersion of the possible values of the random variable around the expected value. The variance itself is defined in terms of two expectations: it is the expected value of the squared deviation of the variable's value from the variable's expected value (var(X) = E(X2) - [E(X)]2).
The expected value plays important roles in a variety of contexts. In regression analysis, one desires a formula in terms of observed data that will give a "good" estimate of the parameter giving the effect of some explanatory variable upon a dependent variable. The formula will give different estimates using different samples of data, so the estimate it gives is itself a random variable. A formula is typically considered good in this context if it is an unbiased estimator— that is if the expected value of the estimate (the average value it would give over an arbitrarily large number of separate samples) can be shown to equal the true value of the desired parameter.
In decision theory, and in particular in choice under uncertainty, an agent is described as making an optimal choice in the context of incomplete information. For risk neutral agents, the choice involves using the expected values of uncertain quantities, while for risk averse agents it involves maximizing the expected value of some objective function such as a von Neumann–Morgenstern utility function. One example of using expected value in reaching optimal decisions is the Gordon–Loeb model of information security investment. According to the model, one can conclude that the amount a firm spends to protect information should generally be only a small fraction of the expected loss (i.e., the expected value of the loss resulting from a cyber or information security breach).Formula E
Formula E is a class of motorsport that uses only electric-powered cars. The series was conceived in 2011, and the inaugural championship commenced in Beijing in September 2014. The series is currently in its fifth season. It is sanctioned by the FIA. Alejandro Agag is the founder and current chairman of Formula E Holdings.List of highest mountains on Earth
There are at least 109 mountains on Earth with elevations greater than 7,200 metres (23,622 ft) above sea level. The vast majority of these mountains are located on the edge of the Indian and Eurasian continental plates. Only those summits are included that, by an objective measure, may be considered individual mountains as opposed to subsidiary peaks.Mass–energy equivalence
In physics, mass–energy equivalence states that anything having mass has an equivalent amount of energy and vice versa, with these fundamental quantities directly relating to one another by Albert Einstein's famous formula:
This formula states that the equivalent energy (E) can be calculated as the mass (m) multiplied by the speed of light (c = ~3×108 m/s) squared. Similarly, anything having energy exhibits a corresponding mass m given by its energy E divided by the speed of light squared c2. Because the speed of light is a very large number in everyday units, the formula implies that even an everyday object at rest with a modest amount of mass has a very large amount of energy intrinsically. Chemical reactions, nuclear reactions, and other energy transformations may cause a system to lose some of its energy content (and thus some corresponding mass), releasing it as the radiant energy of light or as thermal energy for example.
Mass–energy equivalence arose originally from special relativity as a paradox described by Henri Poincaré. Einstein proposed it on 21 November 1905, in the paper Does the inertia of a body depend upon its energy-content?, one of his Annus Mirabilis (Miraculous Year) papers. Einstein was the first to propose that the equivalence of mass and energy is a general principle and a consequence of the symmetries of space and time.
A consequence of the mass–energy equivalence is that if a body is stationary, it still has some internal or intrinsic energy, called its rest energy, corresponding to its rest mass. When the body is in motion, its total energy is greater than its rest energy, and equivalently its total mass (also called relativistic mass in this context) is greater than its rest mass. This rest mass is also called the intrinsic or invariant mass because it remains the same regardless of this motion, even for the extreme speeds or gravity considered in special and general relativity.
The mass–energy formula also serves to convert units of mass to units of energy (and vice versa), no matter what system of measurement units is used.Orders of magnitude (length)
The following are examples of orders of magnitude for different lengths.R.E.M.
R.E.M. was an American rock band from Athens, Georgia, formed in 1980 by drummer Bill Berry, guitarist Peter Buck, bassist/backing vocalist Mike Mills, and lead vocalist Michael Stipe. One of the first alternative rock bands, R.E.M. was noted for Buck's ringing, arpeggiated guitar style, Stipe's distinctive vocal quality and obscure lyrics, Mills' melodic basslines and backing vocals, and Berry's tight, economical style of drumming. R.E.M. released its first single—"Radio Free Europe"—in 1981 on the independent record label Hib-Tone. The single was followed by the Chronic Town EP in 1982, the band's first release on I.R.S. Records. In 1983, the group released its critically acclaimed debut album, Murmur, and built its reputation over the next few years through subsequent releases, constant touring, and the support of college radio. Following years of underground success, R.E.M. achieved a mainstream hit in 1987 with the single "The One I Love". The group signed to Warner Bros. Records in 1988, and began to espouse political and environmental concerns while playing large arenas worldwide.
By the early 1990s, when alternative rock began to experience broad mainstream success, R.E.M. was viewed by subsequent acts such as Nirvana and Pavement as a pioneer of the genre. The band then released its two most commercially successful albums, Out of Time (1991) and Automatic for the People (1992), which veered from the band's established sound and catapulted it to international fame. R.E.M.'s 1994 release, Monster, was a return to a more rock-oriented sound, but still continued its run of success. The band began its first tour in six years to support the album; the tour was marred by medical emergencies suffered by three of the band members.
In 1996, R.E.M. re-signed with Warner Bros. for a reported US$80 million, at the time the most expensive recording contract in history. Its 1996 release, New Adventures in Hi-Fi, though critically acclaimed, fared worse commercially than its predecessors. The following year, Bill Berry left the band, while Stipe, Buck, and Mills continued the group as a trio. Through some changes in musical style, the band continued its career into the next decade with mixed critical and commercial success, despite having sold more than 85 million records worldwide and becoming one of the world's best-selling music artists of all time. In 2007, the band was inducted into the Rock and Roll Hall of Fame, in their first year of eligibility. R.E.M. disbanded in September 2011, announcing the split on its website.S.H.I.E.L.D.
S.H.I.E.L.D. is a fictional espionage, special law enforcement, and counter-terrorism agency appearing in American comic books published by Marvel Comics. Created by Stan Lee and Jack Kirby in Strange Tales #135 (Aug. 1965), it often deals with paranormal and superhuman threats.
The acronym originally stood for Supreme Headquarters, International Espionage and Law-Enforcement Division. It was changed in 1991 to Strategic Hazard Intervention Espionage Logistics Directorate. Within the various films set in the Marvel Cinematic Universe, as well as multiple animated and live-action television series, the backronym stands for Strategic Homeland Intervention, Enforcement and Logistics Division.The organization has heavily appeared in media adaptations as well as films and shows that take place in the Marvel Cinematic Universe.Victory in Europe Day
Victory in Europe Day, generally known as VE Day (Great Britain) or V-E Day (North America), is a day celebrating the formal acceptance by the Allies of World War II of Nazi Germany's unconditional surrender of its armed forces on the 8 May 1945.
The term VE Day existed as early as September 1944, in anticipation of victory. On 30 April 1945, Adolf Hitler, the Nazi leader, committed suicide during the Battle of Berlin. Germany's surrender, therefore, was authorised by his successor, Reichspräsident Karl Dönitz. The administration headed by Dönitz was known as the Flensburg Government. The act of military surrender was first signed at 02:41 on 7 May in SHAEF HQ at Reims, and a slightly modified document was signed on 8 May in Berlin.
European countries celebrate the end of World War II on 8 May. Russia, Belarus, and Serbia celebrate on 9 May, as did several former Soviet bloc countries until after the fall of Communism and the break-up of the Soviet Union. Israel marks VE Day on 9 May as well as a result of the large number of immigrants from the former Soviet Bloc, although it is not a public holiday.Vitamin E
Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitamin E, can cause nerve problems. The crucial function played by Vitamin E that makes it a vitamin is poorly understood, but may involve antioxidant functions in cell membranes. Other theories hold that vitamin E – specifically the RRR stereoisomer of alpha-tocopherol – act by controlling gene expression and cell signal transduction.Worldwide, government organizations recommend adults consume in the range of 7 to 15 mg per day. As of 2016, consumption was below recommendations according to a worldwide summary of more than one hundred studies that reported a median dietary intake of 6.2 mg per day for alpha-tocopherol. Research with alpha-tocopherol as a dietary supplement, with daily amounts as high as 2000 mg per day, has had mixed results. Population studies suggested that people who consumed foods with more vitamin E, or who chose on their own to consume a vitamin E dietary supplement, had lower incidence of cardiovascular diseases, cancer, dementia, and other diseases, but placebo-controlled clinical trials could not always replicate these findings, and there were some indications that vitamin E supplementation actually was associated with a modest increase in all-cause mortality. As of 2017, vitamin E continues to be a topic of active clinical research. Although people commonly apply Vitamin E oil to their skin to try to improve wound healing and reduce scar tissue, reviews have repeatedly concluded that there is no good evidence that this is helpful.Both the tocopherols and tocotrienols occur in α (alpha), β (beta), γ (gamma) and δ (delta) forms, as determined by the number and position of methyl groups on the chromanol ring. All eight of these vitamers feature a chromane double ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals, and a hydrophobic side chain which allows for penetration into biological membranes. Of the many different forms of vitamin E, gamma-tocopherol (γ-tocopherol) is the most common form found in the North American diet, but alpha-tocopherol (α-tocopherol) is the most biologically active. Palm oil is a source of tocotrienols.
Vitamin E was discovered in 1922, isolated in 1935 and first synthesized in 1938. Because the vitamin activity was first identified as essential for fertilized eggs to result in live births (in rats), it was given the name "tocopherol" from Greek words meaning birth and to bear or carry. Alpha-tocopherol, either naturally extracted from plant oils or synthetic, is sold as a popular dietary supplement, either by itself or incorporated into a multivitamin product, and in oils or lotions for use on skin.WALL-E
WALL-E (stylized with an interpunct as WALL·E) is a 2008 American computer-animated science fiction film produced by Pixar Animation Studios for Walt Disney Pictures. It was directed and co-written by Andrew Stanton, produced by Jim Morris, and co-written by Jim Reardon. It stars the voices of Ben Burtt, Elissa Knight, Jeff Garlin, Fred Willard, John Ratzenberger, Kathy Najimy and Sigourney Weaver, and was the overall ninth feature film produced by the company. It follows a solitary trash compactor robot on a future, uninhabitable, deserted Earth, left to clean up garbage. However, he is visited by a probe sent by the starship Axiom, whom he falls in love with and pursues across the galaxy.
After directing Finding Nemo, Stanton felt Pixar had created believable simulations of underwater physics and was willing to direct a film set largely in space. WALL-E has minimal dialogue in its early sequences; many of the characters do not have voices, but instead communicate with body language and robotic sounds designed by Burtt. The film criticizes consumerism, corporatism, nostalgia, waste management, human environmental impact and concerns, obesity, and global catastrophic risk. It is also Pixar's first animated film with segments featuring live-action characters. Following Pixar tradition, WALL-E was paired with a short film titled Presto for its theatrical release.
WALL-E was released in the United States on June 27, 2008. The film was an instant blockbuster, grossing $533.3 million worldwide over a $180 million budget, and winning the 2008 Golden Globe Award for Best Animated Feature Film, the 2009 Hugo Award for Best Long Form Dramatic Presentation, the final Nebula Award for Best Script, the Saturn Award for Best Animated Film and the Academy Award for Best Animated Feature with five nominations. It is considered by many fans and critics as the best film of 2008. The film also topped Time's list of the "Best Movies of the Decade", and in 2016 was voted 29th among 100 films considered the best of the 21st century by 117 film critics from around the world.
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