Charles made a rapid career in the Roman Catholic hierarchy. He was bishop of Nevers (1540–1545), bishop of Saintes (1545–1550, elevated to cardinal in 1548), archbishop of Rouen (1550–1590), bishop of Nantes (1550–1554), Papal legate in Avignon (1565–1590) and bishop of Beauvais (1569–1575). Following the massacre at Wassy and with tensions rising between Guise and Conde forces in Paris, Catherine de' Medici appointed him governor of Paris. Charles attempted to get both to leave Paris to no avail. On 31 December 1578 he was made the first commander in the Order of the Holy Spirit.
When the duke of Alençon and Anjou died childless in 1584 while King Henry III of France was also still childless it was clear that the house of Valois would come to an end with the death of the king and the succession to the French throne would then pass to the house of Bourbon-Vendôme who were descended from Louis IX. However, the senior member of the family, Henry III of Navarre (son of Charles's late elder brother Antoine), was a Protestant. The Catholic League, party to the French Wars of Religion, excluded all Protestants from the succession, which made Charles de Bourbon their champion. In the secret Treaty of Joinville of 31 December 1584 he was recognized by the leaders of the league and a representative of Philip II of Spain as the heir to Henry III of France. Henry III had Charles imprisoned in the castle of Blois on 23 December 1588. He was transferred from one castle to another, presumably to prevent escape. On Henry III's death in 1589, the League proclaimed Charles king, while he was still a prisoner and in the castle of Chinon. He was recognized as Charles X by the parlement of Paris on 21 November 1589. His prison was considered too close to Catholic territory, so he was again transferred, this time to Fontenay-le-Comte. The Catholic League issued coins in his name from 2 August 1589 to his death from 15 Mints, including Paris. Charles, however, renounced the royal title and recognized his nephew Henry IV, whose succession was disputed by the Catholic League. He died in the castle of Fontenay-le-Comte.
Events from the year 1590 in FranceLouis, Prince of Condé (1530–1569)
Louis I de Bourbon, Prince of Condé (7 May 1530 – 13 March 1569) was a prominent Huguenot leader and general, the founder of the House of Condé, a cadet branch of the House of Bourbon.