Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention (CDC) is the leading national public health institute of the United States. The CDC is a United States federal agency under the Department of Health and Human Services and is headquartered in Atlanta, Georgia.[1]

Its main goal is to protect public health and safety through the control and prevention of disease, injury, and disability in the US and internationally.[2] The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. In addition, the CDC researches and provides information on non-infectious diseases such as obesity and diabetes and is a founding member of the International Association of National Public Health Institutes.[3]

Centers for Disease Control and Prevention
US CDC logo
Agency overview
FormedJuly 1, 1946
Preceding agencies
  • Office of National Defense Malaria Control Activities (1942)
  • Office of Malaria Control in War Areas (1942–1946)
  • Communicable Disease Center (1946–1967)
  • National Communicable Disease Center (1967–1970)
  • Center for Disease Control (1970–1980)
  • Centers for Disease Control (1980–1992)
JurisdictionFederal government of the United States
HeadquartersAtlanta, Georgia, U.S.
33°47′56″N 84°19′32″W / 33.7988°N 84.3256°WCoordinates: 33°47′56″N 84°19′32″W / 33.7988°N 84.3256°W
Employees15,000
Annual budgetUS$11.1 billion (FY18)
Agency executive
Parent agencyUnited States Department of Health and Human Services
WebsiteCDC.gov

History

CDC HDR I
CDC headquarters in Atlanta, Georgia, as seen from Emory University
CDC Headquarters PHIL 10693
CDC's Roybal campus in Atlanta, Georgia
Arlen Specter Headquarters Building PHIL 7971
Arlen Specter Headquarters and Emergency Operations Center
Tom Harkin Global Communications Center PHIL 8876
Tom Harkin Global Communications Center
Preparing to enter Ebola treatment unit
CDC and MSF staff preparing to enter an Ebola treatment unit in Liberia, August 2014

The Communicable Disease Center was founded July 1, 1946, as the successor to the World War II Malaria Control in War Areas program[4] of the Office of National Defense Malaria Control Activities.[5]

Preceding its founding, organizations with global influence in malaria control were the Malaria Commission of the League of Nations and the Rockefeller Foundation.[6] The Rockefeller Foundation greatly supported malaria control,[6] sought to have the governments take over some of its efforts, and collaborated with the agency.[7]

The new agency was a branch of the U.S. Public Health Service and Atlanta was chosen as the location because malaria was endemic in the Southern United States.[8] The agency changed names (see infobox on top) before adopting the name Communicable Disease Center in 1946. Offices were located on the sixth floor of the Volunteer Building on Peachtree Street.

With a budget at the time of about $1 million, 59 percent of its personnel were engaged in mosquito abatement and habitat control with the objective of control and eradication of malaria in the United States[9] (see National Malaria Eradication Program).

Among its 369 employees, the main jobs at CDC were originally entomology and engineering. In CDC's initial years, more than six and a half million homes were sprayed, mostly with DDT. In 1946, there were only seven medical officers on duty and an early organization chart was drawn, somewhat fancifully, in the shape of a mosquito. Under Joseph Walter Mountin, the CDC continued to advocate for public health issues and pushed to extend its responsibilities to many other communicable diseases.[10]

In 1947, the CDC made a token payment of $10 to Emory University for 15 acres (61,000 m2) of land on Clifton Road in DeKalb County, still the home of CDC headquarters today. CDC employees collected the money to make the purchase. The benefactor behind the “gift” was Robert W. Woodruff, chairman of the board of The Coca-Cola Company. Woodruff had a long-time interest in malaria control, which had been a problem in areas where he went hunting. The same year, the PHS transferred its San Francisco based plague laboratory into the CDC as the Epidemiology Division, and a new Veterinary Diseases Division was established.[4] An Epidemic Intelligence Service (EIS) was established in 1951, originally due to biological warfare concerns arising from the Korean War; it evolved into two-year postgraduate training program in epidemiology, and a prototype for Field Epidemiology Training Programs (FETP), now found in numerous countries, reflecting CDC's influence in promoting this model internationally.[11]

The mission of CDC expanded beyond its original focus on malaria to include sexually transmitted diseases when the Venereal Disease Division of the U.S. Public Health Service (PHS) was transferred to the CDC in 1957. Shortly thereafter, Tuberculosis Control was transferred (in 1960) to the CDC from PHS, and then in 1963 the Immunization program was established.[12]

It became the National Communicable Disease Center (NCDC) effective July 1, 1967.[5] The organization was renamed the Center for Disease Control (CDC) on June 24, 1970, and Centers for Disease Control effective October 14, 1980.[5] An act of the United States Congress appended the words "and Prevention" to the name effective October 27, 1992. However, Congress directed that the initialism CDC be retained because of its name recognition.[13]

Currently the CDC focus has broadened to include chronic diseases, disabilities, injury control, workplace hazards, environmental health threats, and terrorism preparedness. CDC combats emerging diseases and other health risks, including birth defects, West Nile virus, obesity, avian, swine, and pandemic flu, E. coli, and bioterrorism, to name a few. The organization would also prove to be an important factor in preventing the abuse of penicillin. In May 1994 the CDC admitted having sent several biological warfare agents to the Iraqi government from 1984 through 1989, including Botulinum toxin, West Nile virus, Yersinia pestis and Dengue fever virus.[14]

On April 21, 2005, then–CDC Director Julie Gerberding formally announced the reorganization of CDC to "confront the challenges of 21st-century health threats".[15] The four Coordinating Centers—established under the G. W. Bush Administration and Gerberding—"diminished the influence of national centers under [their] umbrella", and were ordered cut under the Obama Administration in 2009.[16]

Today, the CDC's Biosafety Level 4 laboratories are among the few that exist in the world,[17] and serve as one of only two official repositories of smallpox in the world. The second smallpox store resides at the State Research Center of Virology and Biotechnology VECTOR in the Russian Federation. The CDC revealed in 2014 that it had discovered several misplaced smallpox samples and also that lab workers had potentially been infected with anthrax.[18]

Organization

The CDC is organized into "Centers, Institutes, and Offices" (CIOs), with each organizational unit implementing the agency's activities in a particular area of expertise while also providing intra-agency support and resource-sharing for cross-cutting issues and specific health threats. Generally, CDC "Offices" are subdivided into Centers, which in turn are composed of Divisions and Branches.[19] However, the Center for Global Health and the National Institute for Occupational Safety and Health are freestanding organizational units and do not belong to a parent Office.

The current CIOs are:

The Office of Public Health Preparedness was created during the 2001 anthrax attacks shortly after the terrorist attacks of September 11, 2001. Its purpose was to coordinate among the government the response to a range of biological terrorism threats.[20]

Budget and operations

CDC’s budget for fiscal year 2018 is $11.9 billion.[21]

In addition to its Atlanta headquarters, the CDC has other locations in the United States and Puerto Rico. Those locations include Anchorage; Cleveland; Cincinnati; Detroit; Fort Collins; Hyattsville; Morgantown; Pittsburgh; Research Triangle Park; San Juan, Puerto Rico; Spokane, Washington; and Washington, D.C.

The CDC offers grants that help many organizations each year advance health, safety and awareness at the community level throughout the United States. The CDC awards over 85 percent of its annual budget through these grants.[22]

Workforce

As of 2008, CDC staff numbered approximately 15,000 (including 6,000 contractors and 840 Commissioned Corps officers) in 170 occupations. Eighty percent held bachelor's degrees or higher; almost half had advanced degrees (a master's degree or a doctorate such as a PhD, D.O., or M.D.).[23]

Common CDC job titles include engineer, entomologist, epidemiologist, biologist, physician, veterinarian, behavioral scientist, nurse, medical technologist, economist, public health advisor, health communicator, toxicologist, chemist, computer scientist, and statistician.[24]

The CDC also operates a number of notable training and fellowship programs, including those indicated below.

Epidemic Intelligence Service (EIS)

The Epidemic Intelligence Service (EIS) is composed of "boots-on-the-ground disease detectives" who investigate public health problems domestically and globally.[25] When called upon by a governmental body, EIS officers may embark on short-term epidemiological assistance assignments, or "Epi-Aids", to provide technical expertise in containing and investigating disease outbreaks.[26][27][28] The EIS program is a model for the international Field Epidemiology Training Program.

Public Health Associates Program

The CDC also operates the Public Health Associate Program (PHAP), a two-year paid fellowship for recent college graduates to work in public health agencies all over the United States. PHAP was founded in 2007 and currently has 159 associates in 34 states.[29]

Leadership

David J. Sencer
David Sencer points to a depiction of Triatomine sp., which transmits Chagas disease.

The Director of CDC is a Senior Executive Service position[30] that may be filled either by a career employee, or as a political appointment that does not require Senate confirmation, with the latter method typically being used. The director serves at the pleasure of the President and may be fired at any time.[31][32][33] The CDC director concurrently serves as the Administrator of the Agency for Toxic Substances and Disease Registry.[34]

Sixteen directors have served the CDC or its predecessor agencies.[35][36]

Datasets and survey systems

Areas of focus

Smallpox eradication team
Donald Henderson as part of the CDC's smallpox eradication team in 1966.

Communicable diseases

The CDC's programs address more than 400 diseases, health threats, and conditions that are major causes of death, disease, and disability. The CDC's website has information on various infectious (and noninfectious) diseases, including smallpox, measles, and others.

Influenza

The CDC has launched campaigns targeting the transmission of influenza, including the H1N1 swine flu, and launched websites to educate people in proper hygiene.[45]

Division of Select Agents and Toxins

Within the division are two programs: the Federal Select Agent Program (FSAP) and the Import Permit Program. The FSAP is run jointly with an office within the U.S. Department of Agriculture, regulating agents that can cause disease in humans, animals, and plants. The Import Permit Program regulates the importation of "infectious biological materials."[46]

The CDC runs a program that protects the public from rare and dangerous substances such as anthrax and the Ebola virus. The program, called the Federal Select Agent Program, calls for inspections of labs in the U.S. that work with dangerous pathogens.[47]

During the 2014 Ebola outbreak in West Africa, the CDC helped coordinate the return of two infected American aid workers for treatment at Emory University Hospital, the home of a special unit to handle highly infectious diseases.[48]

As a response to the 2014 Ebola outbreak, Congress passed a Continuing Appropriations Resolution allocating $30,000,000 towards CDC's efforts to fight the virus.[49]

Non-communicable diseases

The CDC also works on non-communicable diseases, including chronic diseases caused by obesity, physical inactivity and tobacco-use.[50]

Antibiotic resistance

The CDC implemented their National Action Plan for Combating Antibiotic Resistant Bacteria as a measure against the spread of antibiotic resistance in the United States. This initiative has a budget of $161 million and includes the development of the Antibiotic Resistance Lab Network.[51]

Global health

The CDC works with other organizations around the world to address global health challenges and contain disease threats at their source. It works closely with many international organizations such as the World Health Organization (WHO) as well as ministries of health and other groups on the front lines of outbreaks. The agency maintains staff in more than 60 countries, including some from the U.S. but even more from the countries in which it operates.[52] The agency's global divisions include the Division of Global HIV and TB (DGHT), the Division of Parasitic Diseases and Malaria (DPDM), the Division of Global Health Protection (DGHP), and the Global Immunization Division (GID).[53]

The CDC is integral in working with the WHO to implement the International Health Regulations (IHR), a legally binding agreement between 196 countries to prevent, control, and report on the international spread of disease, through initiatives including the Global Disease Detection Program (GDD).[54]

The CDC is also a lead implementer of key U.S. global health initiatives such as the President's Emergency Plan for AIDS Relief (PEPFAR) and the President's Malaria Initiative.[55]

Travelers' health

The CDC collects and publishes health information for travelers in a comprehensive book, CDC Health Information for International Travel, which is commonly known as the "yellow book."[56] The book is available online and in print as a new edition every other year and includes current travel health guidelines, vaccine recommendations, and information on specific travel destinations. The CDC also issues travel health notices on its website, consisting of three levels:

"Watch": Level 1 (practice usual precautions)

"Alert": Level 2 (practice enhanced precautions)

"Warning": Level 3 (avoid nonessential travel)[57]

Foundation

The CDC Foundation operates independently from CDC as a private, nonprofit 501(c)(3) organization incorporated in the State of Georgia. The creation of the Foundation was authorized by section 399F of the Public Health Service Act to support the mission of CDC in partnership with the private sector, including organizations, foundations, businesses, educational groups, and individuals.[58][59]

Popular culture and controversies

Historically, the CDC has been relatively free of political manipulation.[60]

Tuskegee Study of Untreated Syphilis in the Negro Male

For 15 years, the CDC had direct oversight over the Tuskegee syphilis experiment.[61] In the study, which lasted from 1932 to 1972, a group of African American men (nearly 400 of whom had syphilis) were studied to learn more about the disease. Notably, the disease was left untreated in the research subjects and they never gave their informed consent to serve as research subjects. The Tuskegee Study was initiated in 1932 by the Public Health Service. The CDC took over the study in 1957.[62]

The CDC's response to the AIDS crisis in the 1980s has been criticized for promoting some public health policies that harmed HIV+ people and for providing ineffective public education. The agency's response to the 2001 anthrax attacks was also criticized for ineffective communication with other public health agencies and with the public.[60]

CDC zombie apocalypse outreach campaign

On May 16, 2011, the Centers for Disease Control and Prevention's blog published an article instructing the public on what to do to prepare for a zombie invasion. While the article did not claim that such a scenario was possible, it did use the popular culture appeal as a means of urging citizens to prepare for all potential hazards, such as earthquakes, tornadoes, and floods.[63]

According to David Daigle, the Associate Director for Communications, Public Health Preparedness and Response, the idea arose when his team was discussing their upcoming hurricane-information campaign and Daigle mused that "we say pretty much the same things every year, in the same way, and I just wonder how many people are paying attention." A social-media employee mentioned that the subject of zombies had come up a lot on Twitter when she had been tweeting about the Fukushima Daiichi nuclear disaster and radiation. The team realized that a campaign like this would most likely reach a different audience from the one that normally pays attention to hurricane-preparedness warnings and went to work on the zombie campaign, launching it right before hurricane season began. "The whole idea was, if you're prepared for a zombie apocalypse, you're prepared for pretty much anything," said Daigle.[64]

Once the blog article became popular, the CDC announced an open contest for YouTube submissions of the most creative and effective videos covering preparedness for a zombie apocalypse (or apocalypse of any kind), to be judged by the "CDC Zombie Task Force". Submissions were open until October 11, 2011.[65] They also released a zombie-themed graphic novella available on their website.[66] Zombie-themed educational materials for teachers are available on the site.[67]

Gun violence

One area of current partisan dispute related to CDC funding is studying gun violence. The 1996 Dickey Amendment states "none of the funds made available for injury prevention and control at the Centers for Disease Control and Prevention may be used to advocate or promote gun control".[68] Advocates for gun control oppose the amendment and have tried to overturn it.[69]

In 1992, Mark L. Rosenberg and five CDC colleagues founded the CDC’s National Center for Injury Prevention and Control, with an annual budget of c. $260,000 that focused on "identifying the root causes of firearm deaths and the best methods to prevent them".[70] Their first report which was published in the New England Journal of Medicine in 1993, entitled "Gun Ownership as a Risk Factor for Homicide in the Home" reported that the "mere presence of a gun in a home increased the risk of a firearm-related death by 2.7 percent, and suicide fivefold—a "huge" increase."[70] In response, the NRA launched a "campaign to shut down the Injury Center." Doctors for Responsible Gun Ownership and Doctors for Integrity and Policy Research joined the pro-gun effort and by 1995, politicians also supported the pro-gun initiative. In 1996, Jay Dickey (R) Arkansas introduced the Dickey Amendment statement "which stated "none of the funds made available for injury prevention and control at the Centers for Disease Control and Prevention may be used to advocate or promote gun control" as a rider[68] in the 1996 appropriations bill."[70] In 1997, "Congress redirected all of the money previously earmarked for gun violence research to the study of traumatic brain injury."[70] David Satcher, who was the CDC head from 1993 to 1998[71] advocated for gun violence research until he left in 1998. In 1999 Rosenberg was fired.[70] Over a dozen "public health insiders, including current and former CDC senior leaders" told The Trace interviewers that CDC senior leaders took an overly cautious stance in their interpretation of the Dickey amendment. They could have done much more.[70] Rosenberg told The Trace in 2016, "Right now, there is nothing stopping them from addressing this life-and-death national problem.”[70]

The American Medical Association, the American Psychological Association and the American Academy of Pediatrics sent a letter to the leaders of the Senate Appropriations Committee in 2013 asking them "to support at least $10 million within the Centers for Disease Control and Prevention (CDC) in FY 2014 along with sufficient new funding at the National Institutes of Health to support research into the causes and prevention of gun violence. Furthermore, we urge Members to oppose any efforts to reduce, eliminate, or condition CDC funding related to gun violence prevention research."[72] Congress maintained the ban in subsequent budgets.[69]

Language guidelines

In December 2017, The Washington Post reported that the Trump administration had issued a list of seven words that were forbidden in official CDC documentation.[73][74] Yuval Levin, after contacting HHS officials, wrote in National Review that the Post story was not accurate.[75][76][77]

Publications

See also

References

Citations

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Sources

  •  This article incorporates public domain material from websites or documents of the Centers for Disease Control and Prevention.

External links

A Pox on Our House

"A Pox on Our House" is the seventh episode of the seventh season of the American medical drama House. It aired on November 15, 2010.

Abortion statistics in the United States

Abortions are conducted in all 50 states, but abortions are more common in some states than they are in others. The Guttmacher Institute did a study that shows which 25 states have the most abortions. States vary widely in terms of overall population, so the total abortions are presented in terms of abortions per 1000 women between the ages of 15 and 45. This list includes totals from 25 states in 2008 and includes states that did not send data to the Center for Disease Control that year. For example, California and Florida had a combined total of 308,550 abortions in 2008 and did not send a report to the CDC that year. Delaware has the most abortions per 1000 women(15-44) at 40. Tennessee had the 25th most with 15.5 per 1000 women(15-44). The median number value is 19.2 abortions per 1000 women (15-44) and corresponds with Kansas at 13th highest. The mean value for the top 25 states with the highest abortions in 2008 is 23.31 abortions per 1000 women (15-44). The total abortions conducted in 2008 in these 25 states with the most abortions is over 1 million.

Centers for Disease Control and Prevention timeline

The following is a timeline of events relating to the Centers for Disease Control and Prevention.

Division of Select Agents and Toxins

The Division of Select Agents and Toxins (DSAT) of the Centers for Disease Control and Prevention is responsible for the Select Agent Program and the Etiologic Agent Import Permit Program. They inspect the laboratories of more than 300 organizations approved to use and transfer select agents, and put regulations in place to minimize risk in the use of these bacterial agents and toxins.DSAT investigates incidents related to the laboratory use of select agents and toxins and refers cases to the FBI and HHS Office of Inspector General when necessary.They also review experiments that are deemed "restricted experiments" because of their increased risk.Samuel S. Edwin became the director of the division in 2016. The office's 2016 budget was approximately $21.5 million.

Dog bite prevention

Dog bite prevention is the effort to educate the public about how to prevent being attacked and bitten by a dog or dogs. In the United States, approximately 4.5 million dog bites occur each year and up to 800,000 people are treated for dog bites annually. About half are children. Young children are typically bitten by familiar or family dogs during normal activities. Some people, like the very young or the very old are more susceptible to being bitten and therefore may need additional methods of prevention.In addition to causing pain, injury, or nerve damage, almost one out of five bites becomes infected, placing the bite victim at risk for illness or death. Those who work and live around dogs should be aware of the risk and take precautions. Rabies is a particular risk associated with dog bites. In the United States between 16,000–39,000 people come in contact with potentially rabid dogs and other animals and receive rabies pre- and postexposure prophylaxis against the rabies virus each year. Because anyone who is bitten by an unvaccinated dog is at risk of getting rabies, local animal control agencies or police are sometimes able to capture the animal and determine whether or not it is infected with rabies.

Emerging Infectious Diseases (journal)

Emerging Infectious Diseases (EID) is an open-access, peer-reviewed journal published by the Centers for Disease Control and Prevention (CDC). EID is a public domain journal and covers global instances of new and reemerging infectious diseases, putting greater emphasis on disease emergence, prevention, control, and elimination. According to Journal Citation Reports, the journal's 2016 impact factor is 6.99, ranking it 4th out of 82 journals in the infectious disease category. The journal also has a 2016 Google Scholar h5-index score of 79, ranking it 2nd in both the epidemiology category and among open-access epidemiological journals, as well as 4th in the communicable diseases category and 1st among open-access communicable disease journals.

Feline zoonosis

Feline zoonosis are the viral, bacterial, fungal, protozoan, nematode and arthropod infections that can be transmitted to humans from the domesticated cat, Felis catus. Some of these are diseases are reemerging and newly emerging infections or infestations caused by zoonotic pathogens transmitted by cats. In some instances, the cat can display symptoms of infection (these may differ from the symptoms in humans) and sometimes the cat remains asymptomatic. There can be serious illnesses and clinical manifestations in people who become infected. This is dependent on the immune status and age of the person. Those who live in close association with cats are more prone to these infections. But those that do not keep cats as pets are also able to acquire these infections because of the transmission can be from cat feces and the parasites that leave their bodies.People can acquire cat-associated infections through bites, scratches or other direct contact of the skin or mucous membranes with the cat. This includes 'kissing' or letting the animal lick the mouth or nose. Mucous membranes are easily infected when the pathogen is in the mouth of the cat. Pathogens can also infect people when there is contact with animal saliva, urine and other body fluids or secretions, When fecal material is unintentionally ingested, infection can occur. Feline zooinosis can be acquired by a person by inhalation of aerosols or droplets coughed up by the cat.In the United States, thirty-two percent of homes have at least one cat. Some contagious infections such as campylobacteriosis and salmonellosis cause visible symptoms of the disease in cats. Other infections, such as cat scratch disease and toxoplasmosis, have no visible symptoms and are carried by apparently healthy cats.

Influenza A virus subtype H1N2

H1N2 is a subtype of the species Influenza A virus (sometimes called bird flu virus). It is currently endemic in both human and pig populations.

H1N1, H1N2, and H3N2 are the only known Influenza A virus subtypes currently circulating among humans.

The virus does not cause more severe illness than other influenza viruses, and no unusual increases in influenza activity have been associated with it.

Linda Saltzman

Linda Ellen Saltzman (September 8, 1949 – March 9, 2005) was an American public health researcher who worked at the Centers for Disease Control (CDC) from 1984 until her death in 2005. She was especially known for her research on domestic violence, which has been credited with helping to define the entire field. She has been described as "...one of the CDC’s top experts on violence, and one of the violence prevention movement’s most trusted allies." In 2007, the CDC established the Linda Saltzman New Investigator Award in her memory; it is awarded biennially to a new researcher in the field of domestic violence.

National Center for Health Statistics

The National Center for Health Statistics (NCHS) is a principal agency of the U.S. Federal Statistical System which provides statistical information to guide actions and policies to improve the health of the American people.

NCHS is housed within the Centers for Disease Control and Prevention (CDC), which is part of the United States Department of Health and Human Services (HHS). It is headquartered at University Town Center in Hyattsville, Maryland, just outside Washington, D.C.

National Institute for Occupational Safety and Health

The National Institute for Occupational Safety and Health (NIOSH, ) is the United States federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. NIOSH is part of the Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services.

NIOSH is headquartered in Washington, D.C., with research laboratories and offices in Cincinnati, Ohio; Morgantown, West Virginia; Pittsburgh, Pennsylvania; Denver, Colorado; Anchorage, Alaska; Spokane, Washington; and Atlanta, Georgia. NIOSH is a professionally diverse organization with a staff of 1,200 people representing a wide range of disciplines including epidemiology, medicine, industrial hygiene, safety, psychology, engineering, chemistry, and statistics.

The director of NIOSH is John Howard.

The Occupational Safety and Health Act, signed by President Richard M. Nixon, on December 29, 1970, created both NIOSH and the Occupational Safety and Health Administration (OSHA). NIOSH was established to help ensure safe and healthful working conditions by providing research, information, education, and training in the field of occupational safety and health. NIOSH provides national and world leadership to prevent work-related illness, injury, disability, and death by gathering information, conducting scientific research, and translating the knowledge gained into products and services.

National Malaria Eradication Program

In the United States, the National Malaria Eradication Program (NMEP) was launched on 1 July 1947. This federal program – with state and local participation – had succeeded in eradicating malaria in the United States by 1951.

Occupational hazard

An occupational hazard is a hazard experienced in the workplace. Occupational hazards can encompass many types of hazards, including chemical hazards, biological hazards (biohazards), psychosocial hazards, and physical hazards. In the United States, the National Institute for Occupational Safety and Health (NIOSH) conduct workplace investigations and research addressing workplace health and safety hazards resulting in guidelines. The Occupational Safety and Health Administration (OSHA) establishes enforceable standards to prevent workplace injuries and illnesses. In the EU a similar role is taken by EU-OSHA.

Occupational hazard as a term signifies both long-term and short-term risks associated with the workplace environment and is a field of study within occupational safety and health and public health. Short term risks may include physical injury, while long-term risks may be increased risk of developing cancer or heart disease.

Pasteurella

Pasteurella is a genus of Gram-negative, facultatively anaerobic bacteria. Pasteurella species are nonmotile and pleomorphic, and often exhibit bipolar staining ("safety pin" appearance). Most species are catalase- and oxidase-positive.

The genus is named after the French chemist and microbiologist, Louis Pasteur, who first identified the bacteria now known as Pasteurella multocida as the agent of chicken cholera.

Strategic National Stockpile

The Strategic National Stockpile (SNS) is the United States' national repository of antibiotics, vaccines, chemical antidotes, antitoxins, and other critical medical supplies. When state, local, tribal, and territorial responders request federal assistance to support their response efforts, the stockpile ensures that the right medicines and supplies get to those who need them most during an emergency. Organized for scalable response to a variety of public health threats, this repository contains enough supplies to respond to multiple large-scale emergencies simultaneously. The Office of the Assistant Secretary for Preparedness and Response (ASPR) of the Department of Health and Human Services, has managed the Strategic National Stockpile since October 1, 2018. Prior to that, the Stockpile was managed by the Centers for Disease Control and Prevention (CDC).

Trichophyton

Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia. Macroconidia are mostly borne laterally directly on the hyphae or on short pedicels, and are thin- or thick-walled, clavate to fusiform, and range from 4 to 8 by 8 to 50 μm in size. Macroconidia are few or absent in many species. Microconidia are spherical, pyriform to clavate or of irregular shape, and range from 2 to 3 by 2 to 4 μm in size.

Vaccine Adverse Event Reporting System

The Vaccine Adverse Event Reporting System (VAERS) is a United States program for vaccine safety, co-managed by the U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA). VAERS is a postmarketing surveillance program, collecting information about adverse events (possible harmful side effects) that occur after administration of vaccines to ascertain whether the risk–benefit ratio is high enough to justify continued use of any particular vaccine.

VAERS, the Vaccine Safety Datalink, and the Clinical Immunization Safety Assessment (CISA) Network are tools by which the CDC and FDA measure vaccine safety to fulfill their duty as regulatory agencies charged with protecting the public. Some scientists would like to do a more scientifically rigorous job of this, noting that VAERS has several limitations, including unverified reports, underreporting, inconsistent data quality, and absence of an unvaccinated control group.

Vaccine Safety Datalink

The Vaccine Safety Datalink Project (VSD) was established in 1990 by the United States Centers for Disease Control and Prevention (CDC) to study the adverse effects of vaccines.

Four large health maintenance organizations, including Kaiser Permanente, were initially recruited to provide the CDC with medical data on vaccination histories, health outcomes, and subject characteristics. The VSD database contains data compiled from surveillance on more than seven million people in the United States, including about 500,000 children from birth through age six years (2% of the U.S. population in this age group).The VSD data-sharing program is now being administered by the National Center for Health Statistics Research Data Center. The data sharing guidelines have been revised to include comments from interested groups as well as recommendations from the Institute of Medicine (IOM).

The Vaccine Adverse Event Reporting System (VAERS), the VSD, and the Clinical Immunization Safety Assessment (CISA) Network are tools by which the CDC and FDA measure vaccine safety to fulfill their duty as regulatory agencies charged with protecting the public. Data from the VSD Project have been utilized to address a number of vaccine safety concerns; examples include a study clarifying the risk of anaphylaxis after vaccine administration and several studies examining the rejected hypothesis of a link between thimerosal-containing vaccines and autism.

Viral disease

A viral disease (or viral infection or infectious disease), occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells.

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