Bill McPherson is a former American football coach in the National Football League. He was the San Francisco 49ers defensive coordinator from 1989 to 1993. He was a coach or front office executive in the 49ers organization from 1979 to 2005 and won five Super Bowls.
McPherson was most known for his ability to coach the defensive line, serving as coach of that position for Santa Clara University (1963–1974), UCLA (1975–1977), Philadelphia Eagles (1978), and San Francisco 49ers (1979–1991, 1994–1998). While with Santa Clara, he also served as linebackers coach and associate head coach.
Bill McPherson may refer to:
Bill McPherson (1897–1976), Scottish-American soccer player
Bill McPherson (American football) (fl. 1979–2005), San Francisco 49ers defensive coordinator
Bill McPherson (footballer, born 1884), Scottish footballer for Liverpool F.C.