Alkermes (company)

Alkermes plc is a biopharmaceutical company that focuses on central nervous system (CNS) diseases. The company is the result of a merger in September 2011 between Alkermes, Inc., and Elan Drug Technologies (EDT), the former drug formulation and manufacturing division of Élan Corporation, plc.[3] The company is headquartered in Dublin, and has an R&D center in Waltham, Massachusetts, and manufacturing facilities in Athlone, Ireland, and Wilmington, Ohio.[1]

Alkermes plc
Russell 1000 Component
Key people
Richard Pops, CEO
RevenueIncrease US$1 (2018) billion[2]
Decrease US$-42.9 Million
Decrease US$-39.6 Million
Total assetsDecrease US$452 Million
Total equityDecrease US$392 Million
Number of employees


Alkermes has more than 20 commercial drug products and candidates that address serious and chronic diseases, such as addiction, schizophrenia, diabetes and depression. Among these products, five are primary to the company: risperidone long-acting Injection (generic for Risperdal Consta) for schizophrenia and bipolar 1 disorder,[4][5] paliperidone palmitate (generic for Invega Sustenna in the U.S., Xeplion in Europe) for schizophrenia,[6][7] 4-aminopyridine (generic for Ampyra in the U.S., Fampyra in Europe) to improve walking in patients with multiple sclerosis,[8][9] naltrexone for extended-release injectable suspension (generic for Vivitrol) for alcohol and opioid dependence,[10][11] and exenatide extended-release for injectable suspension (generic for Bydureon) for the treatment of type 2 diabetes. Bydureon is a once-weekly, extended-release form of the drug, exenatide (Byetta), and was developed through a partnership between Amylin Pharmaceuticals, Alkermes and Eli Lilly. It is approved in Europe and the U.S.[12]

Buprenorphine/samidorphan (ALKS-5461), a κ-opioid receptor antagonist, is a next-generation, novel antidepressant which is under development by Alkermes for treatment-resistant depression.[13]

Olanzapine/samidorphan (ALKS-3831) is an atypical antipsychotic and opioid modulator combination that is under development for the treatment of schizophrenia and bipolar mania.[14][15]


  1. ^ a b Robert Weisman (10 May 2011). "Alkermes to buy Irish drug maker". Boston Globe. Retrieved 13 October 2011.
  2. ^ "Alkermes (ALKS) Quarterly Report". WikiInvest. 2011. Retrieved 13 October 2011.
  3. ^ "Alkermes Reels In Elan's Drug Technology Business". 9 May 2011. Retrieved 13 October 2011.
  4. ^ Zacks Equity Research, “Positive Data on Risperdal Consta Archived 2012-04-26 at the Wayback Machine,” Yahoo! Finance, March 29, 2011.
  5. ^ John M. Grohol, “Risperdal Consta Approved for Bipolar,”, May 18, 2009.
  6. ^ Cole Petrochko, “FDA Okays First Monthly Antipsychotic Drug,” MedPage Today, August 5, 2009.
  7. ^ Matt Jarzemsky, “Johnson & Johnson Gets European Approval For Schizophrenia Shot,” The Wall Street Journal, March 9, 2011.
  8. ^ Susan Jeffrey, “FDA Approves Dalfampridine to Improve Walking in Multiple Sclerosis,” Medscape Medical News, January 22, 2010.
  9. ^ Toni Clarke, “Europe backs Acorda, Biogen drug in change of tack,” Reuters, May 20, 2011.
  10. ^ Miranda Hitti, “FDA OKs New Drug to Treat Alcoholism,” WebMD, April 14, 2006.
  11. ^ Rita Rubin, “FDA OKs Vivitrol to treat heroin, narcotic addictions,” USA Today, October 13, 2010.
  12. ^ Denise Mann, "Weekly Shot Gets FDA Nod for Type 2 Diabetes," WebMD, January 27, 2012
  13. ^ Harrison, Charlotte (2013). "Trial watch: Opioid receptor blocker shows promise in Phase II depression trial". Nature Reviews Drug Discovery. 12 (6): 415–415. doi:10.1038/nrd4028. ISSN 1474-1776. PMID 23722336.
  14. ^ Maric NP, Jovicic MJ, Mihaljevic M, Miljevic C (2016). "Improving Current Treatments for Schizophrenia". Drug Dev. Res. 77 (7): 357–367. doi:10.1002/ddr.21337. PMID 27633376.
  15. ^ Fellner C (2017). "New Schizophrenia Treatments Address Unmet Clinical Needs". P T. 42 (2): 130–134. PMC 5265239. PMID 28163559.

Alkermes may refer to:

Alkermes (company), a biopharmaceutical company

Alchermes, a red liqueur coloured by inclusion of the insect Kermes vermilio

Pharmaceutical companies of the United States

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